Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic review

Abstract Objectives Although frequently applied, inferior alveolar nerve block (IANB) is associated with high rate of complications, beside its unpredictable success; partly due to improper needle choice. Evidence of the ideal needle contradicts in literature. Therefore, this review aims to assess t...

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Main Authors: Mennat Allah Ashraf Abd-Elsabour, Ayat Gamal-AbdelNaser
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Head & Face Medicine
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Online Access:https://doi.org/10.1186/s13005-025-00481-1
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author Mennat Allah Ashraf Abd-Elsabour
Ayat Gamal-AbdelNaser
author_facet Mennat Allah Ashraf Abd-Elsabour
Ayat Gamal-AbdelNaser
author_sort Mennat Allah Ashraf Abd-Elsabour
collection DOAJ
description Abstract Objectives Although frequently applied, inferior alveolar nerve block (IANB) is associated with high rate of complications, beside its unpredictable success; partly due to improper needle choice. Evidence of the ideal needle contradicts in literature. Therefore, this review aims to assess the effect of needle characteristics on the outcomes of IANB. Materials and methods A systematic search was performed on MedLine via Pubmed, Cochrane Library, LILACS, Science Open, EBSCOhost, Scopus, Egyptian Knowledge Bank (EKB), and Google scholar; beside searching grey literature and hand searching. The review included randomized controlled trials comparing needles of difference in any of the characteristics (gauge, length, bevel, alloy) used for IANB regarding their effects on pain, success of anesthesia and aspiration. The authors ran the search, selected the eligible studies, assessed the risk of bias using RoB 1 and extracted the data of the finally included studies. All the steps were performed in duplicates. Results The search yielded a total of 2,812 records. After de-duplication and excluding ineligible studies by title and abstract then by full text, the review included nine eligible studies. The compared needle interventions included: gauges (23G, 24G, 25G, 26G, 27G and 30G), lengths (12 mm, 25 mm, 32 mm, 35 mm, 42 mm), and internal diameters (0.265 mm, 0.215 mm, 0.3 mm and 0.4 mm). All studies had high risk of bias, adopted different assessment methods for the outcomes, and included participants with differences in baseline characteristics. Conclusions The level of the available evidence introduced by primary studies hinder concluding the optimal needle characteristics; keeping the research question unanswered. However, within the limitations of the heterogenous studies, available data favors thinner needles for less pain during needle insertion; otherwise, data of the other outcomes was inconclusive. Clinical relevance Thinner needles are favored for less pain during insertion; but standardized future studies are essentially needed for solid conclusions. A detailed standard protocol is, therefore, proposed.
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spelling doaj-art-52049f6859ef4b13b4cc4446f5abaef52025-02-09T12:56:23ZengBMCHead & Face Medicine1746-160X2025-02-0121111210.1186/s13005-025-00481-1Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic reviewMennat Allah Ashraf Abd-Elsabour0Ayat Gamal-AbdelNaser1Pediatric and Community Dentistry Department, Faculty of Oral and Dental Medicine, Ahram Canadian UniversityDepartment of Oral Medicine and Periodontology, Faculty of Oral and Dental Medicine, Ahram Canadian UniversityAbstract Objectives Although frequently applied, inferior alveolar nerve block (IANB) is associated with high rate of complications, beside its unpredictable success; partly due to improper needle choice. Evidence of the ideal needle contradicts in literature. Therefore, this review aims to assess the effect of needle characteristics on the outcomes of IANB. Materials and methods A systematic search was performed on MedLine via Pubmed, Cochrane Library, LILACS, Science Open, EBSCOhost, Scopus, Egyptian Knowledge Bank (EKB), and Google scholar; beside searching grey literature and hand searching. The review included randomized controlled trials comparing needles of difference in any of the characteristics (gauge, length, bevel, alloy) used for IANB regarding their effects on pain, success of anesthesia and aspiration. The authors ran the search, selected the eligible studies, assessed the risk of bias using RoB 1 and extracted the data of the finally included studies. All the steps were performed in duplicates. Results The search yielded a total of 2,812 records. After de-duplication and excluding ineligible studies by title and abstract then by full text, the review included nine eligible studies. The compared needle interventions included: gauges (23G, 24G, 25G, 26G, 27G and 30G), lengths (12 mm, 25 mm, 32 mm, 35 mm, 42 mm), and internal diameters (0.265 mm, 0.215 mm, 0.3 mm and 0.4 mm). All studies had high risk of bias, adopted different assessment methods for the outcomes, and included participants with differences in baseline characteristics. Conclusions The level of the available evidence introduced by primary studies hinder concluding the optimal needle characteristics; keeping the research question unanswered. However, within the limitations of the heterogenous studies, available data favors thinner needles for less pain during needle insertion; otherwise, data of the other outcomes was inconclusive. Clinical relevance Thinner needles are favored for less pain during insertion; but standardized future studies are essentially needed for solid conclusions. A detailed standard protocol is, therefore, proposed.https://doi.org/10.1186/s13005-025-00481-1AspirationConventional inferior alveolar nerve blockDental anesthesiaLocal anesthesiaMandibular anesthesia
spellingShingle Mennat Allah Ashraf Abd-Elsabour
Ayat Gamal-AbdelNaser
Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic review
Head & Face Medicine
Aspiration
Conventional inferior alveolar nerve block
Dental anesthesia
Local anesthesia
Mandibular anesthesia
title Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic review
title_full Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic review
title_fullStr Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic review
title_full_unstemmed Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic review
title_short Optimal needle characteristics for classical inferior alveolar nerve block anesthesia: a systematic review
title_sort optimal needle characteristics for classical inferior alveolar nerve block anesthesia a systematic review
topic Aspiration
Conventional inferior alveolar nerve block
Dental anesthesia
Local anesthesia
Mandibular anesthesia
url https://doi.org/10.1186/s13005-025-00481-1
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