Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseases
Wastewater-based epidemiology was utilized during the COVID-19 outbreak to monitor the circulation of SARS-CoV-2, the virus causing this disease. However, this approach is limited by the need for additional methods to accurately translate virus concentrations in wastewater to disease-positive human...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2025-02-01
|
| Series: | Geospatial Health |
| Subjects: | |
| Online Access: | https://www.geospatialhealth.net/gh/article/view/1326 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823856977777786880 |
|---|---|
| author | Néstor DelaPaz-Ruíz Ellen-Wien Augustijn Mahdi Farnaghi Sheheen A. Abdulkareem Raul Zurita Milla |
| author_facet | Néstor DelaPaz-Ruíz Ellen-Wien Augustijn Mahdi Farnaghi Sheheen A. Abdulkareem Raul Zurita Milla |
| author_sort | Néstor DelaPaz-Ruíz |
| collection | DOAJ |
| description |
Wastewater-based epidemiology was utilized during the COVID-19 outbreak to monitor the circulation of SARS-CoV-2, the virus causing this disease. However, this approach is limited by the need for additional methods to accurately translate virus concentrations in wastewater to disease-positive human counts. Combined modelling of COVID-19 disease cases and the concentration of its causative virus, SARS-CoV-2, in wastewater will necessarily deepen our understanding. However, this requires addressing the technical differences between disease, population mobility and wastewater models. To that end, we developed an integrated Agent-Based Model (ABM) that facilitates analysis in space and time at various temporal resolutions, including disease spread, population mobility and wastewater production, while also being sufficiently generic for different types of infectious diseases or pathogens. The integrated model replicates the epidemic curve for COVID-19 and can estimate the daily infections at the household level, enabling the monitoring of the spatial patterns of infection intensity. Additionally, the model allows monitoring the estimated production of infected wastewater over time and spatially across the sewage and treatment plant. The model addresses differences between resolutions and can potentially support Early Warning Systems (EWS) for future pandemics.
|
| format | Article |
| id | doaj-art-532a46df12ca40769d1a0997ba7bdc33 |
| institution | Kabale University |
| issn | 1827-1987 1970-7096 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Geospatial Health |
| spelling | doaj-art-532a46df12ca40769d1a0997ba7bdc332025-02-12T02:57:49ZengPAGEPress PublicationsGeospatial Health1827-19871970-70962025-02-0120110.4081/gh.2025.1326Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseasesNéstor DelaPaz-Ruíz0https://orcid.org/0000-0002-8941-4677Ellen-Wien Augustijn1Mahdi Farnaghi2Sheheen A. Abdulkareem3Raul Zurita Milla4Department of Geo-Information Process (GIP), Faculty of Geo-Information Science and Earth Observation (ITC), University of Twente, EnschedeDepartment of Geo-Information Process (GIP), Faculty of Geo-Information Science and Earth Observation (ITC), University of Twente, EnschedeDepartment of Geo-Information Process (GIP), Faculty of Geo-Information Science and Earth Observation (ITC), University of Twente, EnschedeDepartment of Computer Science, University of Duhok, Duhok, Kurdistan-regionDepartment of Geo-Information Process (GIP), Faculty of Geo-Information Science and Earth Observation (ITC), University of Twente, Enschede Wastewater-based epidemiology was utilized during the COVID-19 outbreak to monitor the circulation of SARS-CoV-2, the virus causing this disease. However, this approach is limited by the need for additional methods to accurately translate virus concentrations in wastewater to disease-positive human counts. Combined modelling of COVID-19 disease cases and the concentration of its causative virus, SARS-CoV-2, in wastewater will necessarily deepen our understanding. However, this requires addressing the technical differences between disease, population mobility and wastewater models. To that end, we developed an integrated Agent-Based Model (ABM) that facilitates analysis in space and time at various temporal resolutions, including disease spread, population mobility and wastewater production, while also being sufficiently generic for different types of infectious diseases or pathogens. The integrated model replicates the epidemic curve for COVID-19 and can estimate the daily infections at the household level, enabling the monitoring of the spatial patterns of infection intensity. Additionally, the model allows monitoring the estimated production of infected wastewater over time and spatially across the sewage and treatment plant. The model addresses differences between resolutions and can potentially support Early Warning Systems (EWS) for future pandemics. https://www.geospatialhealth.net/gh/article/view/1326Agent-based modelepidemiologysurveillanceoutbreakgeospatial |
| spellingShingle | Néstor DelaPaz-Ruíz Ellen-Wien Augustijn Mahdi Farnaghi Sheheen A. Abdulkareem Raul Zurita Milla Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseases Geospatial Health Agent-based model epidemiology surveillance outbreak geospatial |
| title | Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseases |
| title_full | Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseases |
| title_fullStr | Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseases |
| title_full_unstemmed | Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseases |
| title_short | Integrating agent-based disease, mobility and wastewater models for the study of the spread of communicable diseases |
| title_sort | integrating agent based disease mobility and wastewater models for the study of the spread of communicable diseases |
| topic | Agent-based model epidemiology surveillance outbreak geospatial |
| url | https://www.geospatialhealth.net/gh/article/view/1326 |
| work_keys_str_mv | AT nestordelapazruiz integratingagentbaseddiseasemobilityandwastewatermodelsforthestudyofthespreadofcommunicablediseases AT ellenwienaugustijn integratingagentbaseddiseasemobilityandwastewatermodelsforthestudyofthespreadofcommunicablediseases AT mahdifarnaghi integratingagentbaseddiseasemobilityandwastewatermodelsforthestudyofthespreadofcommunicablediseases AT sheheenaabdulkareem integratingagentbaseddiseasemobilityandwastewatermodelsforthestudyofthespreadofcommunicablediseases AT raulzuritamilla integratingagentbaseddiseasemobilityandwastewatermodelsforthestudyofthespreadofcommunicablediseases |