Integral invariant manifold method applied to a mathematical model of osteosarcoma

In this study, an asymptotic method called the method of integral invariant manifold (MIM) was applied to a mathematical model of Osteosarcoma cancer. The mathematical model describes the interactions of the immune system cells and the osteosarcoma tumor. These interactions are described by nonlinea...

Full description

Saved in:
Bibliographic Details
Main Author: Ophir Nave
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Results in Control and Optimization
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666720725000153
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this study, an asymptotic method called the method of integral invariant manifold (MIM) was applied to a mathematical model of Osteosarcoma cancer. The mathematical model describes the interactions of the immune system cells and the osteosarcoma tumor. These interactions are described by nonlinear ordinary differential equations. By applying the MIM method, two critical dynamic variables (Cancer cells and Necrotic cells) were identified, providing insights into the dynamics of osteosarcoma over time during treatment.
ISSN:2666-7207