In-depth imaging of in-vitro tissue models using electrical impedance tomography

This study presents a novel micro-electrode-based measurement system designed for in-depth electrical impedance imaging of in-vitro tissue models. Preliminary study regarding the influence of electrode size and density on imaging quality is carried out in this work. In addition to the measurement a...

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Main Authors: Jian Deng, Babu Linkoon P Meenaketan, Saeedeh Ebrahimi Takalloo, Yoke Chin Cha, Tom Torfs, Dries Braeken, Jan De Beenhouwer, Jan Sijbers
Format: Article
Language:deu
Published: NDT.net 2025-02-01
Series:e-Journal of Nondestructive Testing
Online Access:https://www.ndt.net/search/docs.php3?id=30763
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author Jian Deng
Babu Linkoon P Meenaketan
Saeedeh Ebrahimi Takalloo
Yoke Chin Cha
Tom Torfs
Dries Braeken
Jan De Beenhouwer
Jan Sijbers
author_facet Jian Deng
Babu Linkoon P Meenaketan
Saeedeh Ebrahimi Takalloo
Yoke Chin Cha
Tom Torfs
Dries Braeken
Jan De Beenhouwer
Jan Sijbers
author_sort Jian Deng
collection DOAJ
description This study presents a novel micro-electrode-based measurement system designed for in-depth electrical impedance imaging of in-vitro tissue models. Preliminary study regarding the influence of electrode size and density on imaging quality is carried out in this work. In addition to the measurement apparatus, we introduce a memory-efficient imaging technique capable of producing high-resolution 3D electrical impedance (conductivity) reconstruction. The performance of the proposed system is validated through simulations and experimental evaluations, demonstrating its significant potential for advancing biological research, particularly in applications such as organoid and spheroid culturing.
format Article
id doaj-art-57c209530d9c44219aa619618cec3a99
institution Kabale University
issn 1435-4934
language deu
publishDate 2025-02-01
publisher NDT.net
record_format Article
series e-Journal of Nondestructive Testing
spelling doaj-art-57c209530d9c44219aa619618cec3a992025-02-06T10:48:19ZdeuNDT.nete-Journal of Nondestructive Testing1435-49342025-02-0130210.58286/30763In-depth imaging of in-vitro tissue models using electrical impedance tomographyJian DengBabu Linkoon P MeenaketanSaeedeh Ebrahimi TakallooYoke Chin ChaTom TorfsDries BraekenJan De Beenhouwerhttps://orcid.org/0000-0001-5253-1274Jan Sijbershttps://orcid.org/0000-0003-4225-2487 This study presents a novel micro-electrode-based measurement system designed for in-depth electrical impedance imaging of in-vitro tissue models. Preliminary study regarding the influence of electrode size and density on imaging quality is carried out in this work. In addition to the measurement apparatus, we introduce a memory-efficient imaging technique capable of producing high-resolution 3D electrical impedance (conductivity) reconstruction. The performance of the proposed system is validated through simulations and experimental evaluations, demonstrating its significant potential for advancing biological research, particularly in applications such as organoid and spheroid culturing. https://www.ndt.net/search/docs.php3?id=30763
spellingShingle Jian Deng
Babu Linkoon P Meenaketan
Saeedeh Ebrahimi Takalloo
Yoke Chin Cha
Tom Torfs
Dries Braeken
Jan De Beenhouwer
Jan Sijbers
In-depth imaging of in-vitro tissue models using electrical impedance tomography
e-Journal of Nondestructive Testing
title In-depth imaging of in-vitro tissue models using electrical impedance tomography
title_full In-depth imaging of in-vitro tissue models using electrical impedance tomography
title_fullStr In-depth imaging of in-vitro tissue models using electrical impedance tomography
title_full_unstemmed In-depth imaging of in-vitro tissue models using electrical impedance tomography
title_short In-depth imaging of in-vitro tissue models using electrical impedance tomography
title_sort in depth imaging of in vitro tissue models using electrical impedance tomography
url https://www.ndt.net/search/docs.php3?id=30763
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