Prevalence and risk factors associated with prehypertension in Shunde District, southern China

Objective To explore the prevalence and combined cardiovascular risk factors of prehypertension in southern China.Design A retrospective study; the logistic regression model was used to find the risk factors of prehypertension.Setting The study was conducted in Shunde District, southern China, using...

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Main Authors: Yuli Huang, Yunzhao Hu, Xiaoyan Cai, Wenke Qiu, Changhua Liu, Dingji Zhu, Jinghai Hua, Yanxian Wu, Dingli Xu
Format: Article
Language:English
Published: BMJ Publishing Group 2014-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/4/11/e006551.full
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author Yuli Huang
Yunzhao Hu
Xiaoyan Cai
Wenke Qiu
Changhua Liu
Dingji Zhu
Jinghai Hua
Yanxian Wu
Dingli Xu
author_facet Yuli Huang
Yunzhao Hu
Xiaoyan Cai
Wenke Qiu
Changhua Liu
Dingji Zhu
Jinghai Hua
Yanxian Wu
Dingli Xu
author_sort Yuli Huang
collection DOAJ
description Objective To explore the prevalence and combined cardiovascular risk factors of prehypertension in southern China.Design A retrospective study; the logistic regression model was used to find the risk factors of prehypertension.Setting The study was conducted in Shunde District, southern China, using the community-based health check-up information.Participants Participants aged ≥35 years with complete health check-up information data between January 2011 and December 2013 were enrolled and divided into hypertension, prehypertension and optimal blood pressure (BP) groups. Prehypertension was further divided into low-range (BP 120–129/80–84 mm Hg) and high-range (BP 130–139/85–89 mm Hg) subgroups.Outcome measures The prevalence of prehypertension and the combined cardiovascular risk factors within the prehypertensive subgroups.Results Of the 5362 initially reviewed cases (aged ≥35 years), 651 were excluded because of missing data. The proportions of optimal BP, prehypertension and hypertension were 39.1%, 38.6% and 22.3%, respectively. The average age, proportion of male sex, overweight, impaired fasting glucose (IFG), dyslipidaemia and hyperuricaemia were significantly higher in the prehypertension group than in the optimal BP group (all p <0.05). Compared with low-range prehypertension, the proportions of overweight, dyslipidaemia and IFG were higher in the high-range prehypertension group (all p<0.05). Multivariate logistic regression analysis showed that overweight (OR=2.84, 95% CI 1.55 to 5.20), male sex (OR=2.19, 95% CI 1.39 to 3.45), age (per 10 years, OR=1.21, 95% CI 1.02 to 1.44, p=0.03) and hyperuricaemia (OR=1.70, 95% CI 1.14 to 2.54) were independent risk factors of prehypertension.Conclusions Prehypertension is highly prevalent in southern China. Prehypertensive individuals presented with many other cardiovascular risk factors. There was heterogeneity of combined risk factors within the prehypertensive subgroups.
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spelling doaj-art-586a5d9318884f13b14dc280f78ae4082025-02-11T15:05:08ZengBMJ Publishing GroupBMJ Open2044-60552014-11-0141110.1136/bmjopen-2014-006551Prevalence and risk factors associated with prehypertension in Shunde District, southern ChinaYuli Huang0Yunzhao Hu1Xiaoyan Cai2Wenke Qiu3Changhua Liu4Dingji Zhu5Jinghai Hua6Yanxian Wu7Dingli Xu8Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, People`s Republic of China7 Department of Cardiology, The First People`s Hospital of Shunde, Shunde, China4The Second Affiliated Hospital of South China University of Technology, Guangzhou, ChinaDepartment of Health Management Center, The First People`s Hospital of Shunde, Foshan, People`s Republic of ChinaDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, People`s Republic of ChinaDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, People`s Republic of ChinaDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, People`s Republic of ChinaDepartment of Cardiology, The First People`s Hospital of Shunde, Foshan, People`s Republic of ChinaDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, People`s Republic of ChinaObjective To explore the prevalence and combined cardiovascular risk factors of prehypertension in southern China.Design A retrospective study; the logistic regression model was used to find the risk factors of prehypertension.Setting The study was conducted in Shunde District, southern China, using the community-based health check-up information.Participants Participants aged ≥35 years with complete health check-up information data between January 2011 and December 2013 were enrolled and divided into hypertension, prehypertension and optimal blood pressure (BP) groups. Prehypertension was further divided into low-range (BP 120–129/80–84 mm Hg) and high-range (BP 130–139/85–89 mm Hg) subgroups.Outcome measures The prevalence of prehypertension and the combined cardiovascular risk factors within the prehypertensive subgroups.Results Of the 5362 initially reviewed cases (aged ≥35 years), 651 were excluded because of missing data. The proportions of optimal BP, prehypertension and hypertension were 39.1%, 38.6% and 22.3%, respectively. The average age, proportion of male sex, overweight, impaired fasting glucose (IFG), dyslipidaemia and hyperuricaemia were significantly higher in the prehypertension group than in the optimal BP group (all p <0.05). Compared with low-range prehypertension, the proportions of overweight, dyslipidaemia and IFG were higher in the high-range prehypertension group (all p<0.05). Multivariate logistic regression analysis showed that overweight (OR=2.84, 95% CI 1.55 to 5.20), male sex (OR=2.19, 95% CI 1.39 to 3.45), age (per 10 years, OR=1.21, 95% CI 1.02 to 1.44, p=0.03) and hyperuricaemia (OR=1.70, 95% CI 1.14 to 2.54) were independent risk factors of prehypertension.Conclusions Prehypertension is highly prevalent in southern China. Prehypertensive individuals presented with many other cardiovascular risk factors. There was heterogeneity of combined risk factors within the prehypertensive subgroups.https://bmjopen.bmj.com/content/4/11/e006551.full
spellingShingle Yuli Huang
Yunzhao Hu
Xiaoyan Cai
Wenke Qiu
Changhua Liu
Dingji Zhu
Jinghai Hua
Yanxian Wu
Dingli Xu
Prevalence and risk factors associated with prehypertension in Shunde District, southern China
BMJ Open
title Prevalence and risk factors associated with prehypertension in Shunde District, southern China
title_full Prevalence and risk factors associated with prehypertension in Shunde District, southern China
title_fullStr Prevalence and risk factors associated with prehypertension in Shunde District, southern China
title_full_unstemmed Prevalence and risk factors associated with prehypertension in Shunde District, southern China
title_short Prevalence and risk factors associated with prehypertension in Shunde District, southern China
title_sort prevalence and risk factors associated with prehypertension in shunde district southern china
url https://bmjopen.bmj.com/content/4/11/e006551.full
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