Increased miRNA-375 causes oxidative damage but promotes apoptosis resistance and cell migration in the clam Ruditapes philippinarum

Increased miRNA-375 causes oxidative damage but promotes apoptosis resistance and cell migration in the clam Ruditapes philippinarum

MicroRNA is an important regulatory factor at the post-transcriptional level. Previous miRNAomics analysis found that miRNA-375 was steadily upregulated in the clam Ruditapes philippinarum upon ammonia nitrogen exposure. However, we have no knowledge about its regulatory mechanism yet. In this study...

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Bibliographic Details
Main Authors: Ming Cong, Zhaoshun Li, Wenwen Tian, Yixian Yu, Yu Che, Jiasen Lv
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Marine Science
Subjects:
Ruditapes philippinarum
miRNA-375
NH3-N exposure
oxidative damage
apoptosis resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmars.2025.1528020/full
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