Mechanical properties and microbial assessment of additively manufactured diamond and gyroid Ti-6Al-4V ELI scaffolds for interbody fusion cages applications

This study investigates the mechanical behaviour and microbial assessment of additively manufactured porous titanium scaffolds for interbody fusion cages applications. This study is meticulously designed to focus on both the mechanical and microbial assessments. Two types of cubic porous structure s...

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Main Authors: Mohit Kumar, Vijay Kumar Meena, Suman Singh
Format: Article
Language:English
Published: IOP Publishing 2025-01-01
Series:Materials Research Express
Subjects:
Online Access:https://doi.org/10.1088/2053-1591/adaac4
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author Mohit Kumar
Vijay Kumar Meena
Suman Singh
author_facet Mohit Kumar
Vijay Kumar Meena
Suman Singh
author_sort Mohit Kumar
collection DOAJ
description This study investigates the mechanical behaviour and microbial assessment of additively manufactured porous titanium scaffolds for interbody fusion cages applications. This study is meticulously designed to focus on both the mechanical and microbial assessments. Two types of cubic porous structure scaffolds were manufactured. The type 1 scaffold was designed with a diamond structure, featuring a pore size of 500 microns and 65% porosity. Similarly, the type 2 scaffold was designed with a gyroid structure, having a pore size of 500 microns and 65% porosity. Both the types of scaffolds were manufactured using direct selective laser sintering technique. Both the group of scaffolds tested for quasi static compression testing, fatigue compression testing, compression torsional testing and corrosion testing for mechanical properties evaluation. For microbial evaluation, bio burden tests, total organic carbon and total hydrocarbon tests were conducted on the both type of scaffolds. Static compression testing results reported that there is no significant effect on the compression strength properties. Diamond scaffolds had higher yield force value than gyroid scaffolds. Fatigue compression and compression - torsional results reported the higher endurance strength of diamond scaffolds over the gyroid scaffolds. There was no significant difference reported for corrosion behavior of both scaffolds. In the present study, both types of scaffolds demonstrated an almost negligible biological burden. The total organic carbon and hydrocarbons values reported were also under permissible limit as per ISO 19227.Results demonstrated several advantages such as higher endurance strength of diamond scaffolds over gyroid scaffolds, highly corrosion resistance and negligible bio burden limits.
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spelling doaj-art-5a563962bee54aec929807b9d4f5290e2025-02-06T17:13:11ZengIOP PublishingMaterials Research Express2053-15912025-01-0112202650310.1088/2053-1591/adaac4Mechanical properties and microbial assessment of additively manufactured diamond and gyroid Ti-6Al-4V ELI scaffolds for interbody fusion cages applicationsMohit Kumar0https://orcid.org/0000-0002-5974-8772Vijay Kumar Meena1Suman Singh2CSIR- Central Scientific Instruments Organisation, Sector 30-C, Chandigarh, 160030, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India; Auxein Medical Private Limited, Sonipat 131028, IndiaCSIR- Central Scientific Instruments Organisation, Sector 30-C, Chandigarh, 160030, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, IndiaCSIR- Central Scientific Instruments Organisation, Sector 30-C, Chandigarh, 160030, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, IndiaThis study investigates the mechanical behaviour and microbial assessment of additively manufactured porous titanium scaffolds for interbody fusion cages applications. This study is meticulously designed to focus on both the mechanical and microbial assessments. Two types of cubic porous structure scaffolds were manufactured. The type 1 scaffold was designed with a diamond structure, featuring a pore size of 500 microns and 65% porosity. Similarly, the type 2 scaffold was designed with a gyroid structure, having a pore size of 500 microns and 65% porosity. Both the types of scaffolds were manufactured using direct selective laser sintering technique. Both the group of scaffolds tested for quasi static compression testing, fatigue compression testing, compression torsional testing and corrosion testing for mechanical properties evaluation. For microbial evaluation, bio burden tests, total organic carbon and total hydrocarbon tests were conducted on the both type of scaffolds. Static compression testing results reported that there is no significant effect on the compression strength properties. Diamond scaffolds had higher yield force value than gyroid scaffolds. Fatigue compression and compression - torsional results reported the higher endurance strength of diamond scaffolds over the gyroid scaffolds. There was no significant difference reported for corrosion behavior of both scaffolds. In the present study, both types of scaffolds demonstrated an almost negligible biological burden. The total organic carbon and hydrocarbons values reported were also under permissible limit as per ISO 19227.Results demonstrated several advantages such as higher endurance strength of diamond scaffolds over gyroid scaffolds, highly corrosion resistance and negligible bio burden limits.https://doi.org/10.1088/2053-1591/adaac4porous scaffolds3D printingSLMmechanical propertiesmicrobial properties
spellingShingle Mohit Kumar
Vijay Kumar Meena
Suman Singh
Mechanical properties and microbial assessment of additively manufactured diamond and gyroid Ti-6Al-4V ELI scaffolds for interbody fusion cages applications
Materials Research Express
porous scaffolds
3D printing
SLM
mechanical properties
microbial properties
title Mechanical properties and microbial assessment of additively manufactured diamond and gyroid Ti-6Al-4V ELI scaffolds for interbody fusion cages applications
title_full Mechanical properties and microbial assessment of additively manufactured diamond and gyroid Ti-6Al-4V ELI scaffolds for interbody fusion cages applications
title_fullStr Mechanical properties and microbial assessment of additively manufactured diamond and gyroid Ti-6Al-4V ELI scaffolds for interbody fusion cages applications
title_full_unstemmed Mechanical properties and microbial assessment of additively manufactured diamond and gyroid Ti-6Al-4V ELI scaffolds for interbody fusion cages applications
title_short Mechanical properties and microbial assessment of additively manufactured diamond and gyroid Ti-6Al-4V ELI scaffolds for interbody fusion cages applications
title_sort mechanical properties and microbial assessment of additively manufactured diamond and gyroid ti 6al 4v eli scaffolds for interbody fusion cages applications
topic porous scaffolds
3D printing
SLM
mechanical properties
microbial properties
url https://doi.org/10.1088/2053-1591/adaac4
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