Oxidative Stress in Endometrial Flushing Fluid of Patients with Polycystic Ovary Syndrome, Endometrioma and Uterine Leiomyoma: Comparison with Healthy Controls
OBJECTIVE: Polycystic ovary syndrome, myoma uteri and endometrioma are frequently seen gynecologic problems and all three diseases may cause infertility. Aim of this cross-sectional study was to compare total antioxidant status, ceruloplasmin, total sulfhydryl , total oxidant status, lipid hydroper...
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| Format: | Article |
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Medical Network
2020-08-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
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| Online Access: | https://gorm.com.tr/index.php/GORM/article/view/1091 |
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| author | Mustafa Demir Onur Ince Bulent Yilmaz Mert Ulas Barut Ulviye Cansu Ozturk Avni Kılıc Ahmet Berkiz Turp Recep Sutcu Seyithan Taysi |
| author_facet | Mustafa Demir Onur Ince Bulent Yilmaz Mert Ulas Barut Ulviye Cansu Ozturk Avni Kılıc Ahmet Berkiz Turp Recep Sutcu Seyithan Taysi |
| author_sort | Mustafa Demir |
| collection | DOAJ |
| description |
OBJECTIVE: Polycystic ovary syndrome, myoma uteri and endometrioma are frequently seen gynecologic problems and all three diseases may cause infertility. Aim of this cross-sectional study was to compare total antioxidant status, ceruloplasmin, total sulfhydryl , total oxidant status, lipid hydroperoxide and oxidative stress index levels in endometrial flushing fluid of patients with Polycystic ovary syndrome (n=20), uterine leiomyoma (n=20), endometrioma (n=19), and healthy women (n=20).
STUDY DESIGN: We compare endometrial flushing fluid of patients with polycystic ovary syndrome (n=20), uterine leiomyoma (n=20), endometrioma (n=19) and healthy women (n=20). Endometrial flushing fluid samples were collected during the implantation window of all women.
RESULTS: Mean age of groups was 28.90±5.45, 37.25±2.73, 32.84±6.62 and 32.15±5.18 in Polycystic ovary syndrome, myoma uteri, endometrioma and control groups, respectively (p<0.05). Mean total antioxidant status, ceruloplasmin and total sulfhydryl levels indicating antioxidant state were comparable between Polycystic ovary syndrome, myoma uteri, endometrioma and control groups (p=0.806, p=0.156, p=0.328 respectively for markers). Similarly, oxidant state-related markers didn’t differ significantly between 4 groups (p=0.090 for total oxidant status, p=0.087 for lipid hydroperoxide, p=0.312 for oxidative stress index).
CONCLUSION: Endometrial flushing fluid total antioxidant status, total oxidant status, lipid hydroperoxide, ceruloplasmin, and total sulfhydryl levels during implantation window didn’t differ between women with Polycystic ovary syndrome, uterine leiomyoma, endometrioma, and healthy controls.
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| format | Article |
| id | doaj-art-5ca821002312443baa6c1ff71e40f195 |
| institution | Kabale University |
| issn | 1300-4751 2602-4918 |
| language | English |
| publishDate | 2020-08-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj-art-5ca821002312443baa6c1ff71e40f1952025-02-11T21:27:11ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182020-08-0126210.21613/GORM.2020.1091742Oxidative Stress in Endometrial Flushing Fluid of Patients with Polycystic Ovary Syndrome, Endometrioma and Uterine Leiomyoma: Comparison with Healthy ControlsMustafa Demir0Onur Ince1Bulent Yilmaz2Mert Ulas Barut3Ulviye Cansu Ozturk4Avni Kılıc5Ahmet Berkiz Turp6Recep Sutcu7Seyithan Taysi8Anka hospital / GaziantepKutahya Health Science University Faculty of Medicine, Kutahya, TurkeyRecep Tayyip Erdogan University Faculty of Medicine, Rize, TurkeyHarran University Faculty of Medicine, Sanliurfa, TurkeyRecep Tayyip Erdogan University Faculty of Medicine, Rize, TurkeySanliurfa Education and Research Hospital, Sanliurfa, TurkeySilifke State Hospital, Mersin, TurkeyIzmir Katip Celebi University Faculty of Medicine, Izmir,TurkeyGaziantep University, Faculty of Medicine, Gaziantep, Turkey OBJECTIVE: Polycystic ovary syndrome, myoma uteri and endometrioma are frequently seen gynecologic problems and all three diseases may cause infertility. Aim of this cross-sectional study was to compare total antioxidant status, ceruloplasmin, total sulfhydryl , total oxidant status, lipid hydroperoxide and oxidative stress index levels in endometrial flushing fluid of patients with Polycystic ovary syndrome (n=20), uterine leiomyoma (n=20), endometrioma (n=19), and healthy women (n=20). STUDY DESIGN: We compare endometrial flushing fluid of patients with polycystic ovary syndrome (n=20), uterine leiomyoma (n=20), endometrioma (n=19) and healthy women (n=20). Endometrial flushing fluid samples were collected during the implantation window of all women. RESULTS: Mean age of groups was 28.90±5.45, 37.25±2.73, 32.84±6.62 and 32.15±5.18 in Polycystic ovary syndrome, myoma uteri, endometrioma and control groups, respectively (p<0.05). Mean total antioxidant status, ceruloplasmin and total sulfhydryl levels indicating antioxidant state were comparable between Polycystic ovary syndrome, myoma uteri, endometrioma and control groups (p=0.806, p=0.156, p=0.328 respectively for markers). Similarly, oxidant state-related markers didn’t differ significantly between 4 groups (p=0.090 for total oxidant status, p=0.087 for lipid hydroperoxide, p=0.312 for oxidative stress index). CONCLUSION: Endometrial flushing fluid total antioxidant status, total oxidant status, lipid hydroperoxide, ceruloplasmin, and total sulfhydryl levels during implantation window didn’t differ between women with Polycystic ovary syndrome, uterine leiomyoma, endometrioma, and healthy controls. https://gorm.com.tr/index.php/GORM/article/view/1091Endometrial flushing fluid oxidative stressEndometrial receptivityEndometriomaMyoma uteriPolycystic ovary syndrome |
| spellingShingle | Mustafa Demir Onur Ince Bulent Yilmaz Mert Ulas Barut Ulviye Cansu Ozturk Avni Kılıc Ahmet Berkiz Turp Recep Sutcu Seyithan Taysi Oxidative Stress in Endometrial Flushing Fluid of Patients with Polycystic Ovary Syndrome, Endometrioma and Uterine Leiomyoma: Comparison with Healthy Controls Gynecology Obstetrics & Reproductive Medicine Endometrial flushing fluid oxidative stress Endometrial receptivity Endometrioma Myoma uteri Polycystic ovary syndrome |
| title | Oxidative Stress in Endometrial Flushing Fluid of Patients with Polycystic Ovary Syndrome, Endometrioma and Uterine Leiomyoma: Comparison with Healthy Controls |
| title_full | Oxidative Stress in Endometrial Flushing Fluid of Patients with Polycystic Ovary Syndrome, Endometrioma and Uterine Leiomyoma: Comparison with Healthy Controls |
| title_fullStr | Oxidative Stress in Endometrial Flushing Fluid of Patients with Polycystic Ovary Syndrome, Endometrioma and Uterine Leiomyoma: Comparison with Healthy Controls |
| title_full_unstemmed | Oxidative Stress in Endometrial Flushing Fluid of Patients with Polycystic Ovary Syndrome, Endometrioma and Uterine Leiomyoma: Comparison with Healthy Controls |
| title_short | Oxidative Stress in Endometrial Flushing Fluid of Patients with Polycystic Ovary Syndrome, Endometrioma and Uterine Leiomyoma: Comparison with Healthy Controls |
| title_sort | oxidative stress in endometrial flushing fluid of patients with polycystic ovary syndrome endometrioma and uterine leiomyoma comparison with healthy controls |
| topic | Endometrial flushing fluid oxidative stress Endometrial receptivity Endometrioma Myoma uteri Polycystic ovary syndrome |
| url | https://gorm.com.tr/index.php/GORM/article/view/1091 |
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