Idiopathic CD4 lymphocytopenia: An uncommon but fatal cause of Pneumocystis pneumonia
Pneumocystis pneumonia (PCP) is a fungal infection with primary occurrence in immunocompromised individuals by the etiologic agent Pneumocystis jirovecii. In those without previously identified risk factors, maintaining an index of suspicion for this diagnosis with search for underlying immunosuppre...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Respiratory Medicine Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007125000139 |
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| author | Julia Schearer Christopher Merrick |
| author_facet | Julia Schearer Christopher Merrick |
| author_sort | Julia Schearer |
| collection | DOAJ |
| description | Pneumocystis pneumonia (PCP) is a fungal infection with primary occurrence in immunocompromised individuals by the etiologic agent Pneumocystis jirovecii. In those without previously identified risk factors, maintaining an index of suspicion for this diagnosis with search for underlying immunosuppressive cause is of utmost importance. Here, we present a case of fatal PCP in a patient without a known history of immunocompromise subsequently diagnosed with idiopathic CD4 lymphocytopenia (ICL) with an absolute CD4+ T-cell count of 7 cells/uL. |
| format | Article |
| id | doaj-art-5d8bbe3435774637adc306e02643b071 |
| institution | Kabale University |
| issn | 2213-0071 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj-art-5d8bbe3435774637adc306e02643b0712025-02-09T05:00:24ZengElsevierRespiratory Medicine Case Reports2213-00712025-01-0154102177Idiopathic CD4 lymphocytopenia: An uncommon but fatal cause of Pneumocystis pneumoniaJulia Schearer0Christopher Merrick1Rocky Vista University College of Osteopathic Medicine, 8401 S Chambers Rd, Englewood, CO, 80112, USA; Corresponding author.UCHealth Memorial Hospital, Colorado Springs, CO, USAPneumocystis pneumonia (PCP) is a fungal infection with primary occurrence in immunocompromised individuals by the etiologic agent Pneumocystis jirovecii. In those without previously identified risk factors, maintaining an index of suspicion for this diagnosis with search for underlying immunosuppressive cause is of utmost importance. Here, we present a case of fatal PCP in a patient without a known history of immunocompromise subsequently diagnosed with idiopathic CD4 lymphocytopenia (ICL) with an absolute CD4+ T-cell count of 7 cells/uL.http://www.sciencedirect.com/science/article/pii/S2213007125000139 |
| spellingShingle | Julia Schearer Christopher Merrick Idiopathic CD4 lymphocytopenia: An uncommon but fatal cause of Pneumocystis pneumonia Respiratory Medicine Case Reports |
| title | Idiopathic CD4 lymphocytopenia: An uncommon but fatal cause of Pneumocystis pneumonia |
| title_full | Idiopathic CD4 lymphocytopenia: An uncommon but fatal cause of Pneumocystis pneumonia |
| title_fullStr | Idiopathic CD4 lymphocytopenia: An uncommon but fatal cause of Pneumocystis pneumonia |
| title_full_unstemmed | Idiopathic CD4 lymphocytopenia: An uncommon but fatal cause of Pneumocystis pneumonia |
| title_short | Idiopathic CD4 lymphocytopenia: An uncommon but fatal cause of Pneumocystis pneumonia |
| title_sort | idiopathic cd4 lymphocytopenia an uncommon but fatal cause of pneumocystis pneumonia |
| url | http://www.sciencedirect.com/science/article/pii/S2213007125000139 |
| work_keys_str_mv | AT juliaschearer idiopathiccd4lymphocytopeniaanuncommonbutfatalcauseofpneumocystispneumonia AT christophermerrick idiopathiccd4lymphocytopeniaanuncommonbutfatalcauseofpneumocystispneumonia |