Disruption of zinc homeostasis reverses tigecycline resistance in Klebsiella pneumoniae

IntroductionZinc exhibits potent antimicrobial properties due to its ability to compromise bacterial structure and protein functionality, effectively inhibiting and eradicating bacteria. However, bacteria have evolved mechanisms to expel excess zinc ions from their cells, enabling them to thrive in...

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Bibliographic Details
Main Authors: Jinyu Wang, Cuiping Xia, Zhaoxin Xia, Jilu Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1458945/full
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