Handshake antimicrobial stewardship for adult surgical patients
Abstract Objective: Evaluate the effects of handshake stewardship on adult general surgical units. Design: Retrospective quasi-experimental pre- and post-intervention study. Setting: A total of 1,278 bed academic medical center with a level 1 trauma center in St. Louis, Missouri. Patients: A...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2025-01-01
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| Series: | Antimicrobial Stewardship & Healthcare Epidemiology |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2732494X24004984/type/journal_article |
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| _version_ | 1823856584747384832 |
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| author | Abby Kosharek Elizabeth Neuner Emily Welch Spenser January Alice Bewley Kevin Hsueh Sena Sayood |
| author_facet | Abby Kosharek Elizabeth Neuner Emily Welch Spenser January Alice Bewley Kevin Hsueh Sena Sayood |
| author_sort | Abby Kosharek |
| collection | DOAJ |
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Abstract
Objective:
Evaluate the effects of handshake stewardship on adult general surgical units.
Design:
Retrospective quasi-experimental pre- and post-intervention study.
Setting:
A total of 1,278 bed academic medical center with a level 1 trauma center in St. Louis, Missouri.
Patients:
Adults admitted to general surgery units.
Intervention:
Once weekly handshake antimicrobial stewardship rounds were initiated in January 2022 on adult general surgery units. The handshake stewardship team consisted of an infectious diseases (ID) physician and pharmacist who reviewed charts of patients receiving systemic antimicrobials without a formal ID consult. Antimicrobial recommendations were delivered in person to general surgery teams including trauma, geriatric trauma, and emergency/general surgery.
Results:
A total of 1,241 charts were reviewed during the post-implementation period with 391 interventions. Seventy-two percent of those interventions were accepted and the acceptance rate improved over the 18-month post-implementation period. Total antimicrobial usage significantly decreased between the pre- and post-implementation period (608 vs 542 d of therapy/1,000 d present, P = 0.004). An interrupted time series found that there was an immediate (P < 0.001) and sustained (P < 0.001) decrease in antibiotic spectrum index during the post-implementation period. No difference was found for in-hospital mortality between the pre- and post-implementation periods [28 (1%) vs 29 (1%), P = 0.791].
Conclusion:
A once-weekly handshake antimicrobial stewardship program was successfully implemented in general surgery units. Antimicrobial use significantly decreased without negatively impacting hospital mortality.
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| format | Article |
| id | doaj-art-6329fbed3d134d4198ef9c57a9e763c5 |
| institution | Kabale University |
| issn | 2732-494X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Antimicrobial Stewardship & Healthcare Epidemiology |
| spelling | doaj-art-6329fbed3d134d4198ef9c57a9e763c52025-02-12T07:09:20ZengCambridge University PressAntimicrobial Stewardship & Healthcare Epidemiology2732-494X2025-01-01510.1017/ash.2024.498Handshake antimicrobial stewardship for adult surgical patientsAbby Kosharek0Elizabeth Neuner1Emily Welch2Spenser January3Alice Bewley4Kevin Hsueh5https://orcid.org/0000-0002-6606-4491Sena Sayood6https://orcid.org/0000-0002-1993-0764Department of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, USADepartment of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, USADepartment of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, USADepartment of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, USADivision of Infectious Diseases, Washington University School of Medicine in St. Louis, St. Louis, MO, USADivision of Infectious Diseases, Washington University School of Medicine in St. Louis, St. Louis, MO, USADivision of Infectious Diseases, Washington University School of Medicine in St. Louis, St. Louis, MO, USA Abstract Objective: Evaluate the effects of handshake stewardship on adult general surgical units. Design: Retrospective quasi-experimental pre- and post-intervention study. Setting: A total of 1,278 bed academic medical center with a level 1 trauma center in St. Louis, Missouri. Patients: Adults admitted to general surgery units. Intervention: Once weekly handshake antimicrobial stewardship rounds were initiated in January 2022 on adult general surgery units. The handshake stewardship team consisted of an infectious diseases (ID) physician and pharmacist who reviewed charts of patients receiving systemic antimicrobials without a formal ID consult. Antimicrobial recommendations were delivered in person to general surgery teams including trauma, geriatric trauma, and emergency/general surgery. Results: A total of 1,241 charts were reviewed during the post-implementation period with 391 interventions. Seventy-two percent of those interventions were accepted and the acceptance rate improved over the 18-month post-implementation period. Total antimicrobial usage significantly decreased between the pre- and post-implementation period (608 vs 542 d of therapy/1,000 d present, P = 0.004). An interrupted time series found that there was an immediate (P < 0.001) and sustained (P < 0.001) decrease in antibiotic spectrum index during the post-implementation period. No difference was found for in-hospital mortality between the pre- and post-implementation periods [28 (1%) vs 29 (1%), P = 0.791]. Conclusion: A once-weekly handshake antimicrobial stewardship program was successfully implemented in general surgery units. Antimicrobial use significantly decreased without negatively impacting hospital mortality. https://www.cambridge.org/core/product/identifier/S2732494X24004984/type/journal_article |
| spellingShingle | Abby Kosharek Elizabeth Neuner Emily Welch Spenser January Alice Bewley Kevin Hsueh Sena Sayood Handshake antimicrobial stewardship for adult surgical patients Antimicrobial Stewardship & Healthcare Epidemiology |
| title | Handshake antimicrobial stewardship for adult surgical patients |
| title_full | Handshake antimicrobial stewardship for adult surgical patients |
| title_fullStr | Handshake antimicrobial stewardship for adult surgical patients |
| title_full_unstemmed | Handshake antimicrobial stewardship for adult surgical patients |
| title_short | Handshake antimicrobial stewardship for adult surgical patients |
| title_sort | handshake antimicrobial stewardship for adult surgical patients |
| url | https://www.cambridge.org/core/product/identifier/S2732494X24004984/type/journal_article |
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