High order expression dependencies finely resolve cryptic states and subtypes in single cell data
Abstract Single cells are typically typed by clustering into discrete locations in reduced dimensional transcriptome space. Here we introduce Stator, a data-driven method that identifies cell (sub)types and states without relying on cells’ local proximity in transcriptome space. Stator labels the sa...
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Main Authors: | Abel Jansma, Yuelin Yao, Jareth Wolfe, Luigi Del Debbio, Sjoerd V Beentjes, Chris P Ponting, Ava Khamseh |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2025-01-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/s44320-024-00074-1 |
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