Correlation of serum C - reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatment
Background and Objectives: Chronic periodontitis is an infectious disease characterized by inflammation within the supporting tissues of the teeth, progressive attachment loss, and bone loss. C-reactive protein, are acute phase proteins monitored as a marker of inflammatory status. The present stud...
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College Of Dentistry Hawler Medical University
2020-06-01
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| Series: | Erbil Dental Journal |
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| Online Access: | https://edj.hmu.edu.krd/index.php/journal/article/view/82 |
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| author | Arkhawan Ali Abdulhaq Ziwar Ahmed Salih Solaf Abdulqadir Mustafa |
| author_facet | Arkhawan Ali Abdulhaq Ziwar Ahmed Salih Solaf Abdulqadir Mustafa |
| author_sort | Arkhawan Ali Abdulhaq |
| collection | DOAJ |
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Background and Objectives: Chronic periodontitis is an infectious disease characterized by inflammation within the supporting tissues of the teeth, progressive attachment loss, and bone loss. C-reactive protein, are acute phase proteins monitored as a marker of inflammatory status. The present study was performed to determine whether presence of periodontitis and non-surgical periodontal therapy could influence the serum levels of CRP in type II diabetes mellitus disease patients.
Materials and methods: A total of 60 subjects were selected for study. Venous blood samples were taken at base line and 3 months after non-surgical periodontal therapy for the type II diabetic patients with the clinical signs of chronic periodontitis (group I, n=30) and patients with chronic periodontitis having no diabetic mellitus (group II, n=30) to estimate serum C-reactive protein (CRP) level. Clinical parameters such as glycated hemoglobin (HBA1c ≥ 6.5% ), random blood sugar (RBS) and clinical periodontal parameters (Gingival Index, Probing pocket depth, Clinical attachment level and Plaque Index) for the group I and II were measured.
Results: at base line, type II diabetes mellitus patients group I (T2DMCP) were compared to the non-diabetic patients with chronic periodontitis group II (NDMCP) based on the clinical periodontal parameters (GI,PPD, CAL and PI )scores and CRP level, HBA1c , (RBS) with the 3months after treatment. All the result was statically significant except for the GI and PPD scores at base line which was statically non-significant. The result also shows significant decrease in all the periodontal parameters and CRP level at base line as compared to 3months after treatment when group I was compared to group II while there was no significant change in the CRP level in group I and HBA1c in group II at base line as compared to 3months treatment. Conclusion: The present study concludes that total CRP level were decreased after non-surgical periodontal therapy.
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| format | Article |
| id | doaj-art-6553d18695cb4ae48e5ba3c96a59c99b |
| institution | Kabale University |
| issn | 2523-6172 2616-4795 |
| language | English |
| publishDate | 2020-06-01 |
| publisher | College Of Dentistry Hawler Medical University |
| record_format | Article |
| series | Erbil Dental Journal |
| spelling | doaj-art-6553d18695cb4ae48e5ba3c96a59c99b2025-02-10T20:48:44ZengCollege Of Dentistry Hawler Medical UniversityErbil Dental Journal2523-61722616-47952020-06-0131Correlation of serum C - reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatmentArkhawan Ali Abdulhaq0Ziwar Ahmed Salih1Solaf Abdulqadir Mustafa2Periodontics Department, College of Dentistry, Hawler Medical UniversityPeriodontics Department, College of Dentistry, Hawler Medical UniversityPeriodontics Department, College of Dentistry, Hawler Medical University Background and Objectives: Chronic periodontitis is an infectious disease characterized by inflammation within the supporting tissues of the teeth, progressive attachment loss, and bone loss. C-reactive protein, are acute phase proteins monitored as a marker of inflammatory status. The present study was performed to determine whether presence of periodontitis and non-surgical periodontal therapy could influence the serum levels of CRP in type II diabetes mellitus disease patients. Materials and methods: A total of 60 subjects were selected for study. Venous blood samples were taken at base line and 3 months after non-surgical periodontal therapy for the type II diabetic patients with the clinical signs of chronic periodontitis (group I, n=30) and patients with chronic periodontitis having no diabetic mellitus (group II, n=30) to estimate serum C-reactive protein (CRP) level. Clinical parameters such as glycated hemoglobin (HBA1c ≥ 6.5% ), random blood sugar (RBS) and clinical periodontal parameters (Gingival Index, Probing pocket depth, Clinical attachment level and Plaque Index) for the group I and II were measured. Results: at base line, type II diabetes mellitus patients group I (T2DMCP) were compared to the non-diabetic patients with chronic periodontitis group II (NDMCP) based on the clinical periodontal parameters (GI,PPD, CAL and PI )scores and CRP level, HBA1c , (RBS) with the 3months after treatment. All the result was statically significant except for the GI and PPD scores at base line which was statically non-significant. The result also shows significant decrease in all the periodontal parameters and CRP level at base line as compared to 3months after treatment when group I was compared to group II while there was no significant change in the CRP level in group I and HBA1c in group II at base line as compared to 3months treatment. Conclusion: The present study concludes that total CRP level were decreased after non-surgical periodontal therapy. https://edj.hmu.edu.krd/index.php/journal/article/view/82Non-surgical periodontal therapydiabetes mellitusCRP levelchronic periodontitis |
| spellingShingle | Arkhawan Ali Abdulhaq Ziwar Ahmed Salih Solaf Abdulqadir Mustafa Correlation of serum C - reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatment Erbil Dental Journal Non-surgical periodontal therapy diabetes mellitus CRP level chronic periodontitis |
| title | Correlation of serum C - reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatment |
| title_full | Correlation of serum C - reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatment |
| title_fullStr | Correlation of serum C - reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatment |
| title_full_unstemmed | Correlation of serum C - reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatment |
| title_short | Correlation of serum C - reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatment |
| title_sort | correlation of serum c reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatment |
| topic | Non-surgical periodontal therapy diabetes mellitus CRP level chronic periodontitis |
| url | https://edj.hmu.edu.krd/index.php/journal/article/view/82 |
| work_keys_str_mv | AT arkhawanaliabdulhaq correlationofserumcreactiveproteinwithclinicalparametersindiabeticpatientshavingchronicperiodontitisbeforeandaftertreatment AT ziwarahmedsalih correlationofserumcreactiveproteinwithclinicalparametersindiabeticpatientshavingchronicperiodontitisbeforeandaftertreatment AT solafabdulqadirmustafa correlationofserumcreactiveproteinwithclinicalparametersindiabeticpatientshavingchronicperiodontitisbeforeandaftertreatment |