Dyslipidemias in normotensive and hypertensive individuals

:The present work was carried out to compare the effects of age and antihypertensive therapy on lipid profile in hypertensive and normotensive individuals. A total of 150 individuals were used for the study.100 hypertensive under therapy were used and 50 normotensive served as control. Serum lipid (...

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Main Authors: NM Igboh, D Onwubiko, LN Chigbu, CI Emuchey, NK Nnamah, CA Onyesom, EN Agomuo, CA Maduagwuna, KME Iheanacho
Format: Article
Language:English
Published: Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) 2013-07-01
Series:Journal of Applied Sciences and Environmental Management
Online Access:https://www.Ajol.Info/index.php/jasem/article/view/90469
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author NM Igboh
D Onwubiko
LN Chigbu
CI Emuchey
NK Nnamah
CA Onyesom
EN Agomuo
CA Maduagwuna
KME Iheanacho
author_facet NM Igboh
D Onwubiko
LN Chigbu
CI Emuchey
NK Nnamah
CA Onyesom
EN Agomuo
CA Maduagwuna
KME Iheanacho
author_sort NM Igboh
collection DOAJ
description :The present work was carried out to compare the effects of age and antihypertensive therapy on lipid profile in hypertensive and normotensive individuals. A total of 150 individuals were used for the study.100 hypertensive under therapy were used and 50 normotensive served as control. Serum lipid (Cholesterol (T -chol) , triglyceride (TG), Phospholipids (PL),High density lipoprotein( HDL-chol ), Low density lipoprotein( LDLchol) and very low density lipoprotein (VLD L- chol) were biochemical parameters monitored. The normotensive studied had mean age of 50 + 11 years and blood pressure of 117 + 6 / 77+ 6 mmHg. The hypertensive had mean age of 55 + 10 years and blood pressure of 177+25 /103 + 10 mmHg.The study revealed that there was a highly significant effect of age on total cholesterol in hypertensive than normotensive individuals .The mean total cholesterol (T -chol) and triglyceride (TG) were (156+11, and 59 + 4) mg/dl respectively for the normotensives; and hypertensive the means were 166 + 13 for the T –chol and 66+ 7 mg/dl for triglyceride (P<0.05). Similarly, a significant lower phospholipids level of 158+8 mg /dl was obtained for normotensives, hypertensives had a mean (165+ 11 mg/dl, P<0.05). However, HDL-chol was lower in hypertensives (57+ 10) mg/dl than in normotensives (64+ 13) mg/dl). Hypertensive patients also recorded higher mean values of LDL-chol (95+ 17) mg/dl than the normotensives with mean values of 81+ 15 mg/dl for LDL- chol. Marginally higher level of VLD L- chol was observed in hypertensive patients as well compared to normotensive individuals VLD L- chol(13+ 2)mg/dl and 12 + 1 mg/dl for VLD Lchol( P<0.05).
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institution Kabale University
issn 2659-1502
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publishDate 2013-07-01
publisher Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)
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series Journal of Applied Sciences and Environmental Management
spelling doaj-art-673700059e75435e8511be5733313a092025-02-08T19:52:15ZengJoint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)Journal of Applied Sciences and Environmental Management2659-15022659-14992013-07-01171Dyslipidemias in normotensive and hypertensive individualsNM IgbohD OnwubikoLN ChigbuCI EmucheyNK NnamahCA OnyesomEN AgomuoCA MaduagwunaKME Iheanacho:The present work was carried out to compare the effects of age and antihypertensive therapy on lipid profile in hypertensive and normotensive individuals. A total of 150 individuals were used for the study.100 hypertensive under therapy were used and 50 normotensive served as control. Serum lipid (Cholesterol (T -chol) , triglyceride (TG), Phospholipids (PL),High density lipoprotein( HDL-chol ), Low density lipoprotein( LDLchol) and very low density lipoprotein (VLD L- chol) were biochemical parameters monitored. The normotensive studied had mean age of 50 + 11 years and blood pressure of 117 + 6 / 77+ 6 mmHg. The hypertensive had mean age of 55 + 10 years and blood pressure of 177+25 /103 + 10 mmHg.The study revealed that there was a highly significant effect of age on total cholesterol in hypertensive than normotensive individuals .The mean total cholesterol (T -chol) and triglyceride (TG) were (156+11, and 59 + 4) mg/dl respectively for the normotensives; and hypertensive the means were 166 + 13 for the T –chol and 66+ 7 mg/dl for triglyceride (P<0.05). Similarly, a significant lower phospholipids level of 158+8 mg /dl was obtained for normotensives, hypertensives had a mean (165+ 11 mg/dl, P<0.05). However, HDL-chol was lower in hypertensives (57+ 10) mg/dl than in normotensives (64+ 13) mg/dl). Hypertensive patients also recorded higher mean values of LDL-chol (95+ 17) mg/dl than the normotensives with mean values of 81+ 15 mg/dl for LDL- chol. Marginally higher level of VLD L- chol was observed in hypertensive patients as well compared to normotensive individuals VLD L- chol(13+ 2)mg/dl and 12 + 1 mg/dl for VLD Lchol( P<0.05).https://www.Ajol.Info/index.php/jasem/article/view/90469
spellingShingle NM Igboh
D Onwubiko
LN Chigbu
CI Emuchey
NK Nnamah
CA Onyesom
EN Agomuo
CA Maduagwuna
KME Iheanacho
Dyslipidemias in normotensive and hypertensive individuals
Journal of Applied Sciences and Environmental Management
title Dyslipidemias in normotensive and hypertensive individuals
title_full Dyslipidemias in normotensive and hypertensive individuals
title_fullStr Dyslipidemias in normotensive and hypertensive individuals
title_full_unstemmed Dyslipidemias in normotensive and hypertensive individuals
title_short Dyslipidemias in normotensive and hypertensive individuals
title_sort dyslipidemias in normotensive and hypertensive individuals
url https://www.Ajol.Info/index.php/jasem/article/view/90469
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AT nknnamah dyslipidemiasinnormotensiveandhypertensiveindividuals
AT caonyesom dyslipidemiasinnormotensiveandhypertensiveindividuals
AT enagomuo dyslipidemiasinnormotensiveandhypertensiveindividuals
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