Brown-McLean syndrome secondary keratoconus
Abstract Background Brown-McLean Syndrome is a rare clinical condition typically presenting as localized edema involving a 2–3 mm peripheral area of the cornea, which often has undergone intraocular surgery. Case report We present a unique case of unilateral Brown-McLean Syndrome (BMS) with concurre...
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BMC
2025-02-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-025-03885-4 |
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| author | Qi Wan Li Chen Ran Wei Ying-ping Deng Ke Ma Jing Tang |
| author_facet | Qi Wan Li Chen Ran Wei Ying-ping Deng Ke Ma Jing Tang |
| author_sort | Qi Wan |
| collection | DOAJ |
| description | Abstract Background Brown-McLean Syndrome is a rare clinical condition typically presenting as localized edema involving a 2–3 mm peripheral area of the cornea, which often has undergone intraocular surgery. Case report We present a unique case of unilateral Brown-McLean Syndrome (BMS) with concurrent keratoconus in an 18-year-old male patient. The individual sought medical attention due to poor vision in the right eye, which had been unnoticed for a month. Notably, there was no history of ocular surgery or trauma, and the patient did not suffer from any systemic diseases. Clinical examination revealed peripheral corneal edema, extending 2–4 mm from the limbus, exclusively affecting the right eye. Corneal topography indicated the presence of keratoconus, which was an incidental finding during the investigation. Conclusions This case underscores the importance of considering BMS in the differential diagnosis of peripheral corneal edema even in the absence of ocular surgery or trauma. The potential relationship between BMS and keratoconus is explored, suggesting that long-term edema and degeneration of the peripheral cornea could alter its biomechanical properties, leading to deformation and keratoconus. Thorough clinical evaluation and long-term follow-up are crucial in managing such patients. |
| format | Article |
| id | doaj-art-682a618ab1074ac694640dc31f8a50e3 |
| institution | Kabale University |
| issn | 1471-2415 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj-art-682a618ab1074ac694640dc31f8a50e32025-02-09T12:26:19ZengBMCBMC Ophthalmology1471-24152025-02-012511510.1186/s12886-025-03885-4Brown-McLean syndrome secondary keratoconusQi Wan0Li Chen1Ran Wei2Ying-ping Deng3Ke Ma4Jing Tang5Department of Ophthalmology, West China Hospital of Sichuan UniversityDepartment of Ophthalmology, West China Hospital of Sichuan UniversityDepartment of Ophthalmology, West China Hospital of Sichuan UniversityDepartment of Ophthalmology, West China Hospital of Sichuan UniversityDepartment of Ophthalmology, West China Hospital of Sichuan UniversityDepartment of Ophthalmology, West China Hospital of Sichuan UniversityAbstract Background Brown-McLean Syndrome is a rare clinical condition typically presenting as localized edema involving a 2–3 mm peripheral area of the cornea, which often has undergone intraocular surgery. Case report We present a unique case of unilateral Brown-McLean Syndrome (BMS) with concurrent keratoconus in an 18-year-old male patient. The individual sought medical attention due to poor vision in the right eye, which had been unnoticed for a month. Notably, there was no history of ocular surgery or trauma, and the patient did not suffer from any systemic diseases. Clinical examination revealed peripheral corneal edema, extending 2–4 mm from the limbus, exclusively affecting the right eye. Corneal topography indicated the presence of keratoconus, which was an incidental finding during the investigation. Conclusions This case underscores the importance of considering BMS in the differential diagnosis of peripheral corneal edema even in the absence of ocular surgery or trauma. The potential relationship between BMS and keratoconus is explored, suggesting that long-term edema and degeneration of the peripheral cornea could alter its biomechanical properties, leading to deformation and keratoconus. Thorough clinical evaluation and long-term follow-up are crucial in managing such patients.https://doi.org/10.1186/s12886-025-03885-4Brown-McLean SyndromePeripheral edemaCase reportKeratoconus |
| spellingShingle | Qi Wan Li Chen Ran Wei Ying-ping Deng Ke Ma Jing Tang Brown-McLean syndrome secondary keratoconus BMC Ophthalmology Brown-McLean Syndrome Peripheral edema Case report Keratoconus |
| title | Brown-McLean syndrome secondary keratoconus |
| title_full | Brown-McLean syndrome secondary keratoconus |
| title_fullStr | Brown-McLean syndrome secondary keratoconus |
| title_full_unstemmed | Brown-McLean syndrome secondary keratoconus |
| title_short | Brown-McLean syndrome secondary keratoconus |
| title_sort | brown mclean syndrome secondary keratoconus |
| topic | Brown-McLean Syndrome Peripheral edema Case report Keratoconus |
| url | https://doi.org/10.1186/s12886-025-03885-4 |
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