Virus-inspired biogenic delivery system for advancing cancer therapy
Virus-inspired particles have been utilized in various applications, including vaccination, gene therapy, drug therapy, and diagnostics. Biogenic delivery systems imitating the natural structure of viruses are regarded as innovative nanoplatforms used to deliver drug compounds to related sites and t...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2025-03-01
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| Series: | Biomedical Technology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949723X25000017 |
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| author | Di Sun Hao Liang Qianwen Mu Chengchao Chu Gang Liu Chao Liu |
| author_facet | Di Sun Hao Liang Qianwen Mu Chengchao Chu Gang Liu Chao Liu |
| author_sort | Di Sun |
| collection | DOAJ |
| description | Virus-inspired particles have been utilized in various applications, including vaccination, gene therapy, drug therapy, and diagnostics. Biogenic delivery systems imitating the natural structure of viruses are regarded as innovative nanoplatforms used to deliver drug compounds to related sites and target cells in organisms. Among them, the components comprised of virus-like particles (VLPs) derive from the proteins or peptides of the viruses; the glycoproteins on their surface exert significant function as specific targeting. Types of assembled glycoproteins and encapsulated drug molecules confer the complexity and varieties of structure, function, and treatment of VLPs. VLPs lack viral virulence, resulting from a viral genetic material deficiency. In vaccine research, Virus-mimic nanovesicles have been effectively verified against cancer via the immunogenicity and the pharmacological effect of drug molecules delivered to mediate an immune response in the body. This review summarizes the research status of virus-inspired drug delivery platforms for cancer therapy utilization. |
| format | Article |
| id | doaj-art-68f8e98c8eb042dba455994ed1c52db1 |
| institution | Kabale University |
| issn | 2949-723X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Biomedical Technology |
| spelling | doaj-art-68f8e98c8eb042dba455994ed1c52db12025-02-09T05:01:49ZengKeAi Communications Co., Ltd.Biomedical Technology2949-723X2025-03-019100069Virus-inspired biogenic delivery system for advancing cancer therapyDi Sun0Hao Liang1Qianwen Mu2Chengchao Chu3Gang Liu4Chao Liu5Shenzhen Research Institute of Xiamen University, 518000, Shenzhen, China; State Key Laboratory of Stress Biology and Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Xiamen University, 361102, Xiamen, China; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, 361102, Xiamen, ChinaState Key Laboratory of Stress Biology and Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Xiamen University, 361102, Xiamen, China; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, 361102, Xiamen, ChinaState Key Laboratory of Stress Biology and Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Xiamen University, 361102, Xiamen, China; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, 361102, Xiamen, ChinaShenzhen Research Institute of Xiamen University, 518000, Shenzhen, China; Corresponding author.State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, 361102, Xiamen, China; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 361102, Xiamen, China; Corresponding author. State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, 361102, Xiamen, China.Shenzhen Research Institute of Xiamen University, 518000, Shenzhen, China; State Key Laboratory of Stress Biology and Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Xiamen University, 361102, Xiamen, China; Corresponding author. Shenzhen Research Institute of Xiamen University, 518000, Shenzhen, China.Virus-inspired particles have been utilized in various applications, including vaccination, gene therapy, drug therapy, and diagnostics. Biogenic delivery systems imitating the natural structure of viruses are regarded as innovative nanoplatforms used to deliver drug compounds to related sites and target cells in organisms. Among them, the components comprised of virus-like particles (VLPs) derive from the proteins or peptides of the viruses; the glycoproteins on their surface exert significant function as specific targeting. Types of assembled glycoproteins and encapsulated drug molecules confer the complexity and varieties of structure, function, and treatment of VLPs. VLPs lack viral virulence, resulting from a viral genetic material deficiency. In vaccine research, Virus-mimic nanovesicles have been effectively verified against cancer via the immunogenicity and the pharmacological effect of drug molecules delivered to mediate an immune response in the body. This review summarizes the research status of virus-inspired drug delivery platforms for cancer therapy utilization.http://www.sciencedirect.com/science/article/pii/S2949723X25000017Virus-inspired particlesVirus-like particlesCancer therapyDrug delivery |
| spellingShingle | Di Sun Hao Liang Qianwen Mu Chengchao Chu Gang Liu Chao Liu Virus-inspired biogenic delivery system for advancing cancer therapy Biomedical Technology Virus-inspired particles Virus-like particles Cancer therapy Drug delivery |
| title | Virus-inspired biogenic delivery system for advancing cancer therapy |
| title_full | Virus-inspired biogenic delivery system for advancing cancer therapy |
| title_fullStr | Virus-inspired biogenic delivery system for advancing cancer therapy |
| title_full_unstemmed | Virus-inspired biogenic delivery system for advancing cancer therapy |
| title_short | Virus-inspired biogenic delivery system for advancing cancer therapy |
| title_sort | virus inspired biogenic delivery system for advancing cancer therapy |
| topic | Virus-inspired particles Virus-like particles Cancer therapy Drug delivery |
| url | http://www.sciencedirect.com/science/article/pii/S2949723X25000017 |
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