STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment
Background The degree of immune infiltration in tumors, especially CD8+ T cells, greatly impacts patient disease course and response to interventional immunotherapy. Enhancement of tumor infiltrating lymphocyte (TIL) is a critical element of efficacious therapy and one that may be achieved via admin...
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Main Authors: | Walter J Storkus, Ronald J Fecek, Manoj Chelvanambi, Jennifer L Taylor |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2021-02-01
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Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/9/2/e001906.full |
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