A cross-tissue transcriptome-wide association study identified susceptibility genes for age-related macular degeneration

A cross-tissue transcriptome-wide association study identified susceptibility genes for age-related macular degeneration

Abstract Age-related macular degeneration (AMD) is a complex multifactorial disease with a significant genetic component. Despite extensive research efforts, the underlying molecular mechanisms remain elusive, necessitating innovative approaches to identify specific genes involved in the pathogenesi...

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Bibliographic Details
Main Authors: Hongfan Yang, Haofei Huang, Kunlin Pu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
TWAS
Cross-tissue
UTMOST
FUSION
Age-related macular degeneration
Online Access:https://doi.org/10.1038/s41598-025-89246-z
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