Preoperative prediction of IDH genotypes and prognosis in adult-type diffuse gliomas: intratumor heterogeneity habitat analysis using dynamic contrast-enhanced MRI and diffusion-weighted imaging

Preoperative prediction of IDH genotypes and prognosis in adult-type diffuse gliomas: intratumor heterogeneity habitat analysis using dynamic contrast-enhanced MRI and diffusion-weighted imaging

Abstract Background Intratumor heterogeneity (ITH) is a key biological characteristic of gliomas. This study aimed to characterize ITH in adult-type diffuse gliomas and assess the feasibility of using habitat imaging based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusi...

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Bibliographic Details
Main Authors: Xingrui Wang, Zhenhui Xie, Xiaoqing Wang, Yang Song, Shiteng Suo, Yan Ren, Wentao Hu, Yi Zhu, Mengqiu Cao, Yan Zhou
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cancer Imaging
Subjects:
Adult-type diffuse glioma
Intratumor heterogeneity
Isocitrate dehydrogenase
Progression-free survival
Dynamic contrast-enhanced perfusion
Diffusion-weighted imaging
Online Access:https://doi.org/10.1186/s40644-025-00829-5
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