Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child

According to WHO, dengue fever (DF) is currently endemic to more than 100 countries in various regions of Africa, America, and Asia; outbreaks have been reported in Europe. In the Russian Federation, there is a much smaller proportion of children among those infected due to the imported nature of th...

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Main Authors: D.V. Preobrazhenskaia, E.V. Melekhina, Zh.B. Ponezheva
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Respiratory Medicine Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213007124001813
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author D.V. Preobrazhenskaia
E.V. Melekhina
Zh.B. Ponezheva
author_facet D.V. Preobrazhenskaia
E.V. Melekhina
Zh.B. Ponezheva
author_sort D.V. Preobrazhenskaia
collection DOAJ
description According to WHO, dengue fever (DF) is currently endemic to more than 100 countries in various regions of Africa, America, and Asia; outbreaks have been reported in Europe. In the Russian Federation, there is a much smaller proportion of children among those infected due to the imported nature of the infection.We described a clinical case of imported dengue fever in an adolescent girl in Moscow after a 5-day vacation. Despite the fact that during the examination at the hospital in the Maldives, DENV arbovirus antigen was isolated in the blood by immunochromatographic rapid test, the course of the disease had a number of symptoms that did not conform to the classical course of the disease: catarrhal symptoms, cough, elevated C-reactive protein, and radiographic evidences of right-sided maxillary sinusitis. No improvement in the condition was observed despite the therapy administered. Additional examination confirmed an active infection caused by M. pneumoniae. After correction of etiotropic and pathogenetic therapy, the patient was discharged with recovery on day 10 of the disease.After 4 years since the start of the pandemic, an increase in infectious morbidity, particularly DF, has been observed. The proportion of co-infections is increasing. Co-infection of DF and respiratory mycoplasmosis in children may occur masked as an acute respiratory viral infection (ARVI): with intensification of catarrhal and intoxication syndromes and atypical changes in laboratory parameters. All that complicates clinical and laboratory diagnosis and leads to incorrect administration of starting etiotropic therapy.
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spelling doaj-art-6e4a8057cf284b25af37de8f409460912025-02-09T05:00:19ZengElsevierRespiratory Medicine Case Reports2213-00712025-01-0153102158Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a childD.V. Preobrazhenskaia0E.V. Melekhina1Zh.B. Ponezheva2Corresponding author.; Central RI [Research Institute] of Epidemiology, Federal Service for the Oversight of Consumer Protection and Welfare (Rospotrebnadzor), Moscow, RussiaCentral RI [Research Institute] of Epidemiology, Federal Service for the Oversight of Consumer Protection and Welfare (Rospotrebnadzor), Moscow, RussiaCentral RI [Research Institute] of Epidemiology, Federal Service for the Oversight of Consumer Protection and Welfare (Rospotrebnadzor), Moscow, RussiaAccording to WHO, dengue fever (DF) is currently endemic to more than 100 countries in various regions of Africa, America, and Asia; outbreaks have been reported in Europe. In the Russian Federation, there is a much smaller proportion of children among those infected due to the imported nature of the infection.We described a clinical case of imported dengue fever in an adolescent girl in Moscow after a 5-day vacation. Despite the fact that during the examination at the hospital in the Maldives, DENV arbovirus antigen was isolated in the blood by immunochromatographic rapid test, the course of the disease had a number of symptoms that did not conform to the classical course of the disease: catarrhal symptoms, cough, elevated C-reactive protein, and radiographic evidences of right-sided maxillary sinusitis. No improvement in the condition was observed despite the therapy administered. Additional examination confirmed an active infection caused by M. pneumoniae. After correction of etiotropic and pathogenetic therapy, the patient was discharged with recovery on day 10 of the disease.After 4 years since the start of the pandemic, an increase in infectious morbidity, particularly DF, has been observed. The proportion of co-infections is increasing. Co-infection of DF and respiratory mycoplasmosis in children may occur masked as an acute respiratory viral infection (ARVI): with intensification of catarrhal and intoxication syndromes and atypical changes in laboratory parameters. All that complicates clinical and laboratory diagnosis and leads to incorrect administration of starting etiotropic therapy.http://www.sciencedirect.com/science/article/pii/S2213007124001813Dengue feverM. pneumoniae infectionChildrenCo-infectionTherapy for arboviral infections
spellingShingle D.V. Preobrazhenskaia
E.V. Melekhina
Zh.B. Ponezheva
Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child
Respiratory Medicine Case Reports
Dengue fever
M. pneumoniae infection
Children
Co-infection
Therapy for arboviral infections
title Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child
title_full Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child
title_fullStr Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child
title_full_unstemmed Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child
title_short Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child
title_sort clinical case of co infection dengue fever and respiratory mycoplasmosis in a child
topic Dengue fever
M. pneumoniae infection
Children
Co-infection
Therapy for arboviral infections
url http://www.sciencedirect.com/science/article/pii/S2213007124001813
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AT evmelekhina clinicalcaseofcoinfectiondenguefeverandrespiratorymycoplasmosisinachild
AT zhbponezheva clinicalcaseofcoinfectiondenguefeverandrespiratorymycoplasmosisinachild