A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population

The coronavirus disease 2019 (COVID-19) pandemic has placed an immense burden on healthcare systems worldwide. There is intensive research targeted at better understanding of the virus pathogenicity, development of effective treatment strategies and vaccines against COVID-19. It is increasingly bein...

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Main Authors: Kai Chin Poh, Victoria Yu Jia Tay, Sarah Huixin Lin, Huei Leng Chee, Suhitharan Thangavelautham
Format: Article
Language:English
Published: Wolters Kluwer – Medknow Publications 2022-07-01
Series:Singapore Medical Journal
Subjects:
Online Access:https://journals.lww.com/10.11622/smedj.2020174
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author Kai Chin Poh
Victoria Yu Jia Tay
Sarah Huixin Lin
Huei Leng Chee
Suhitharan Thangavelautham
author_facet Kai Chin Poh
Victoria Yu Jia Tay
Sarah Huixin Lin
Huei Leng Chee
Suhitharan Thangavelautham
author_sort Kai Chin Poh
collection DOAJ
description The coronavirus disease 2019 (COVID-19) pandemic has placed an immense burden on healthcare systems worldwide. There is intensive research targeted at better understanding of the virus pathogenicity, development of effective treatment strategies and vaccines against COVID-19. It is increasingly being recognised that the pathogenicity of COVID-19 extends beyond the respiratory system. In severe cases, there can be widespread activation of the immune system, vascular injury and a resultant pro-thrombotic state. Severe COVID-19 is widely regarded as a risk factor for venous thromboembolism. Interim European and American guidelines have been created to guide anticoagulation strategies in COVID-19 patients. However, it is unclear if these guidelines can be extrapolated directly to Asians, in whom there are differences in the baseline risk of thrombosis and bleeding. Our review article aimed to summarise the current understanding of arteriovenous thromboembolic complications in COVID-19 and discuss management strategies for prevention and treatment of thrombotic events in Asian COVID-19 patients.
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institution Kabale University
issn 0037-5675
2737-5935
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publishDate 2022-07-01
publisher Wolters Kluwer – Medknow Publications
record_format Article
series Singapore Medical Journal
spelling doaj-art-6ff8aa0620074366bf6e824ec39f24532025-02-10T05:19:50ZengWolters Kluwer – Medknow PublicationsSingapore Medical Journal0037-56752737-59352022-07-0163735036110.11622/smedj.2020174A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian populationKai Chin PohVictoria Yu Jia TaySarah Huixin LinHuei Leng CheeSuhitharan ThangavelauthamThe coronavirus disease 2019 (COVID-19) pandemic has placed an immense burden on healthcare systems worldwide. There is intensive research targeted at better understanding of the virus pathogenicity, development of effective treatment strategies and vaccines against COVID-19. It is increasingly being recognised that the pathogenicity of COVID-19 extends beyond the respiratory system. In severe cases, there can be widespread activation of the immune system, vascular injury and a resultant pro-thrombotic state. Severe COVID-19 is widely regarded as a risk factor for venous thromboembolism. Interim European and American guidelines have been created to guide anticoagulation strategies in COVID-19 patients. However, it is unclear if these guidelines can be extrapolated directly to Asians, in whom there are differences in the baseline risk of thrombosis and bleeding. Our review article aimed to summarise the current understanding of arteriovenous thromboembolic complications in COVID-19 and discuss management strategies for prevention and treatment of thrombotic events in Asian COVID-19 patients.https://journals.lww.com/10.11622/smedj.2020174anticoagulationcovid-19pulmonary embolismvenous thrombosisvenous thrombotic events
spellingShingle Kai Chin Poh
Victoria Yu Jia Tay
Sarah Huixin Lin
Huei Leng Chee
Suhitharan Thangavelautham
A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population
Singapore Medical Journal
anticoagulation
covid-19
pulmonary embolism
venous thrombosis
venous thrombotic events
title A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population
title_full A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population
title_fullStr A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population
title_full_unstemmed A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population
title_short A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population
title_sort review of covid 19 related thrombosis and anticoagulation strategies specific to the asian population
topic anticoagulation
covid-19
pulmonary embolism
venous thrombosis
venous thrombotic events
url https://journals.lww.com/10.11622/smedj.2020174
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