A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population
The coronavirus disease 2019 (COVID-19) pandemic has placed an immense burden on healthcare systems worldwide. There is intensive research targeted at better understanding of the virus pathogenicity, development of effective treatment strategies and vaccines against COVID-19. It is increasingly bein...
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Format: | Article |
Language: | English |
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Wolters Kluwer – Medknow Publications
2022-07-01
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Series: | Singapore Medical Journal |
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Online Access: | https://journals.lww.com/10.11622/smedj.2020174 |
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author | Kai Chin Poh Victoria Yu Jia Tay Sarah Huixin Lin Huei Leng Chee Suhitharan Thangavelautham |
author_facet | Kai Chin Poh Victoria Yu Jia Tay Sarah Huixin Lin Huei Leng Chee Suhitharan Thangavelautham |
author_sort | Kai Chin Poh |
collection | DOAJ |
description | The coronavirus disease 2019 (COVID-19) pandemic has placed an immense burden on healthcare systems worldwide. There is intensive research targeted at better understanding of the virus pathogenicity, development of effective treatment strategies and vaccines against COVID-19. It is increasingly being recognised that the pathogenicity of COVID-19 extends beyond the respiratory system. In severe cases, there can be widespread activation of the immune system, vascular injury and a resultant pro-thrombotic state. Severe COVID-19 is widely regarded as a risk factor for venous thromboembolism. Interim European and American guidelines have been created to guide anticoagulation strategies in COVID-19 patients. However, it is unclear if these guidelines can be extrapolated directly to Asians, in whom there are differences in the baseline risk of thrombosis and bleeding. Our review article aimed to summarise the current understanding of arteriovenous thromboembolic complications in COVID-19 and discuss management strategies for prevention and treatment of thrombotic events in Asian COVID-19 patients. |
format | Article |
id | doaj-art-6ff8aa0620074366bf6e824ec39f2453 |
institution | Kabale University |
issn | 0037-5675 2737-5935 |
language | English |
publishDate | 2022-07-01 |
publisher | Wolters Kluwer – Medknow Publications |
record_format | Article |
series | Singapore Medical Journal |
spelling | doaj-art-6ff8aa0620074366bf6e824ec39f24532025-02-10T05:19:50ZengWolters Kluwer – Medknow PublicationsSingapore Medical Journal0037-56752737-59352022-07-0163735036110.11622/smedj.2020174A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian populationKai Chin PohVictoria Yu Jia TaySarah Huixin LinHuei Leng CheeSuhitharan ThangavelauthamThe coronavirus disease 2019 (COVID-19) pandemic has placed an immense burden on healthcare systems worldwide. There is intensive research targeted at better understanding of the virus pathogenicity, development of effective treatment strategies and vaccines against COVID-19. It is increasingly being recognised that the pathogenicity of COVID-19 extends beyond the respiratory system. In severe cases, there can be widespread activation of the immune system, vascular injury and a resultant pro-thrombotic state. Severe COVID-19 is widely regarded as a risk factor for venous thromboembolism. Interim European and American guidelines have been created to guide anticoagulation strategies in COVID-19 patients. However, it is unclear if these guidelines can be extrapolated directly to Asians, in whom there are differences in the baseline risk of thrombosis and bleeding. Our review article aimed to summarise the current understanding of arteriovenous thromboembolic complications in COVID-19 and discuss management strategies for prevention and treatment of thrombotic events in Asian COVID-19 patients.https://journals.lww.com/10.11622/smedj.2020174anticoagulationcovid-19pulmonary embolismvenous thrombosisvenous thrombotic events |
spellingShingle | Kai Chin Poh Victoria Yu Jia Tay Sarah Huixin Lin Huei Leng Chee Suhitharan Thangavelautham A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population Singapore Medical Journal anticoagulation covid-19 pulmonary embolism venous thrombosis venous thrombotic events |
title | A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population |
title_full | A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population |
title_fullStr | A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population |
title_full_unstemmed | A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population |
title_short | A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population |
title_sort | review of covid 19 related thrombosis and anticoagulation strategies specific to the asian population |
topic | anticoagulation covid-19 pulmonary embolism venous thrombosis venous thrombotic events |
url | https://journals.lww.com/10.11622/smedj.2020174 |
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