Analysis of the efficacy of multidisciplinary integration based on 3D reconstruction technology for the treatment of gout stone
Abstract Objective This study investigates the efficacy of multidisciplinary fusion therapy based on 3D reconstruction technology for the treatment of gouty stone by comparing the efficacy of multidisciplinary fusion therapy with pharmacologic therapy. Methods This study is a cohort study.Patients w...
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| Format: | Article |
| Language: | English |
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BMC
2025-02-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | https://doi.org/10.1186/s13018-025-05506-8 |
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| author | Shizhe Zhou Zengxiao Zhang Tian Liu Yijun Xu Yuehai Pan Ying Chen |
| author_facet | Shizhe Zhou Zengxiao Zhang Tian Liu Yijun Xu Yuehai Pan Ying Chen |
| author_sort | Shizhe Zhou |
| collection | DOAJ |
| description | Abstract Objective This study investigates the efficacy of multidisciplinary fusion therapy based on 3D reconstruction technology for the treatment of gouty stone by comparing the efficacy of multidisciplinary fusion therapy with pharmacologic therapy. Methods This study is a cohort study.Patients who underwent gout stone surgery at the Affiliated Hospital of Qingdao University from November 2020 to November 2022 were included in this study, totaling 85 to form the MDT surgery group, and matched among gout stone patients in the outpatient clinic during the same period to form the medication group. Patients in the 2 groups were followed up for 6 months to compare baseline and follow-up data. Results Both groups experienced a decrease in uric acid levels and an increase in SF-36 scores during follow-up. After adjusting for confounders, multifactorial logistic regression showed that the uric acid attainment rate of patients in the MDT surgery group was 4.011 times higher than that of the drug group (OR: 4.011, 95% CI: 1.595, 10.086, P = 0.003); the proportion of patients with an increase in SF-36 in the MDT surgery group was 4.976 times higher than that of the drug group (OR: 4.976, 95% CI: 2.243, 11.040, P < 0.001); the proportion of patients treated with high-dose medication in the MDT surgery group was 1.8% of that of patients in the drug group (OR: 0.018, 95% CI: 0.002, 0.148, P < 0.001); and the proportion of patients in the MDT surgery group who developed frequent gout was 2.8% of that in the drug group (OR: 0.028 95% CI: 0.003, 0.2398, P = 0.001). the proportion of patients in the MDT surgery group who developed abnormal liver function was 0.317 times higher than that in the drug group (OR: 0.317, 95% CI: 0.121, 0.831, P = 0.019). Conclusion The multidisciplinary integration of 3D reconstructive techniques for gout stone treatment resulted in an increase in uric acid compliance, a decrease in the frequency of gout and the appearance of liver impairment; and a greater benefit in terms of improvement in the quality of life of the patients after treatment. |
| format | Article |
| id | doaj-art-7098b021f9ef4d2b89dc66c01fc9660a |
| institution | Kabale University |
| issn | 1749-799X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj-art-7098b021f9ef4d2b89dc66c01fc9660a2025-02-09T12:47:06ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2025-02-0120111010.1186/s13018-025-05506-8Analysis of the efficacy of multidisciplinary integration based on 3D reconstruction technology for the treatment of gout stoneShizhe Zhou0Zengxiao Zhang1Tian Liu2Yijun Xu3Yuehai Pan4Ying Chen5Department of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao UniversityDepartment of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao UniversityDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao UniversityDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao UniversityDepartment of Hand and Foot Surgery, The Affiliated Hospital of Qingdao UniversityDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao UniversityAbstract Objective This study investigates the efficacy of multidisciplinary fusion therapy based on 3D reconstruction technology for the treatment of gouty stone by comparing the efficacy of multidisciplinary fusion therapy with pharmacologic therapy. Methods This study is a cohort study.Patients who underwent gout stone surgery at the Affiliated Hospital of Qingdao University from November 2020 to November 2022 were included in this study, totaling 85 to form the MDT surgery group, and matched among gout stone patients in the outpatient clinic during the same period to form the medication group. Patients in the 2 groups were followed up for 6 months to compare baseline and follow-up data. Results Both groups experienced a decrease in uric acid levels and an increase in SF-36 scores during follow-up. After adjusting for confounders, multifactorial logistic regression showed that the uric acid attainment rate of patients in the MDT surgery group was 4.011 times higher than that of the drug group (OR: 4.011, 95% CI: 1.595, 10.086, P = 0.003); the proportion of patients with an increase in SF-36 in the MDT surgery group was 4.976 times higher than that of the drug group (OR: 4.976, 95% CI: 2.243, 11.040, P < 0.001); the proportion of patients treated with high-dose medication in the MDT surgery group was 1.8% of that of patients in the drug group (OR: 0.018, 95% CI: 0.002, 0.148, P < 0.001); and the proportion of patients in the MDT surgery group who developed frequent gout was 2.8% of that in the drug group (OR: 0.028 95% CI: 0.003, 0.2398, P = 0.001). the proportion of patients in the MDT surgery group who developed abnormal liver function was 0.317 times higher than that in the drug group (OR: 0.317, 95% CI: 0.121, 0.831, P = 0.019). Conclusion The multidisciplinary integration of 3D reconstructive techniques for gout stone treatment resulted in an increase in uric acid compliance, a decrease in the frequency of gout and the appearance of liver impairment; and a greater benefit in terms of improvement in the quality of life of the patients after treatment.https://doi.org/10.1186/s13018-025-05506-8Gout stone3D reconstructionSurgicalUric acidSF-36 |
| spellingShingle | Shizhe Zhou Zengxiao Zhang Tian Liu Yijun Xu Yuehai Pan Ying Chen Analysis of the efficacy of multidisciplinary integration based on 3D reconstruction technology for the treatment of gout stone Journal of Orthopaedic Surgery and Research Gout stone 3D reconstruction Surgical Uric acid SF-36 |
| title | Analysis of the efficacy of multidisciplinary integration based on 3D reconstruction technology for the treatment of gout stone |
| title_full | Analysis of the efficacy of multidisciplinary integration based on 3D reconstruction technology for the treatment of gout stone |
| title_fullStr | Analysis of the efficacy of multidisciplinary integration based on 3D reconstruction technology for the treatment of gout stone |
| title_full_unstemmed | Analysis of the efficacy of multidisciplinary integration based on 3D reconstruction technology for the treatment of gout stone |
| title_short | Analysis of the efficacy of multidisciplinary integration based on 3D reconstruction technology for the treatment of gout stone |
| title_sort | analysis of the efficacy of multidisciplinary integration based on 3d reconstruction technology for the treatment of gout stone |
| topic | Gout stone 3D reconstruction Surgical Uric acid SF-36 |
| url | https://doi.org/10.1186/s13018-025-05506-8 |
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