The Role of Human Papilloma Virus in Synchronous Gynecologic Malignancies: A Report of Two Cases and Review of the Literature
Aim of the paper is to investigate the suspicious role of HPV in synchronous endometrial and cervical carcinomas and to discuss the relation between HPV and endometrium epithelium. The first case is 68- year-old and the second case is 56 year-old postmenopausal woman who were diagnosed with invasive...
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| Format: | Article |
| Language: | English |
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Medical Network
2015-04-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
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| Online Access: | https://gorm.com.tr/index.php/GORM/article/view/46 |
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| author | Salih Taşkın Emre Göksan Pabuçcu Alper Kahraman İbrahim Yalçın Uğur Fırat Ortaç |
| author_facet | Salih Taşkın Emre Göksan Pabuçcu Alper Kahraman İbrahim Yalçın Uğur Fırat Ortaç |
| author_sort | Salih Taşkın |
| collection | DOAJ |
| description | Aim of the paper is to investigate the suspicious role of HPV in synchronous endometrial and cervical carcinomas and to discuss the relation between HPV and endometrium epithelium. The first case is 68- year-old and the second case is 56 year-old postmenopausal woman who were diagnosed with invasive cervical carcinoma synchronously with endometrial carcinoma. Following surgical procedures, high risk HPV DNA analysis using PCR were undertaken in both cases to investigate the possible role of HPV in synchronous malignancies. All endometrial samples were considered as negative for high risk HPV types however all cervical samples were considered as positive. Unlike cervical pathologies, HPV does not seem to play active role as etiologic agent in endometrial neoplasms, even detected synchronously with invasive cervical cancers. |
| format | Article |
| id | doaj-art-7226eb6942744f7c9b4398b986483d5b |
| institution | Kabale University |
| issn | 1300-4751 2602-4918 |
| language | English |
| publishDate | 2015-04-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj-art-7226eb6942744f7c9b4398b986483d5b2025-02-11T21:25:20ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182015-04-0121141The Role of Human Papilloma Virus in Synchronous Gynecologic Malignancies: A Report of Two Cases and Review of the LiteratureSalih Taşkın0Emre Göksan Pabuçcu1Alper Kahraman2İbrahim Yalçın3Uğur Fırat Ortaç4Ankara University School of Medicine Department of Obstetrics and Gynecology, AnkaraKaraman State Hospital Department of Obstetrics and Gynecology, KaramanAnkara University School of Medicine Department of Obstetrics and Gynecology, AnkaraAnkara University School of Medicine Department of Obstetrics and Gynecology, AnkaraAnkara University School of Medicine Department of Obstetrics and Gynecology, AnkaraAim of the paper is to investigate the suspicious role of HPV in synchronous endometrial and cervical carcinomas and to discuss the relation between HPV and endometrium epithelium. The first case is 68- year-old and the second case is 56 year-old postmenopausal woman who were diagnosed with invasive cervical carcinoma synchronously with endometrial carcinoma. Following surgical procedures, high risk HPV DNA analysis using PCR were undertaken in both cases to investigate the possible role of HPV in synchronous malignancies. All endometrial samples were considered as negative for high risk HPV types however all cervical samples were considered as positive. Unlike cervical pathologies, HPV does not seem to play active role as etiologic agent in endometrial neoplasms, even detected synchronously with invasive cervical cancers.https://gorm.com.tr/index.php/GORM/article/view/46Cervical carcinomaEndometrial carcinomaHuman papilloma virusSynchronous cancer |
| spellingShingle | Salih Taşkın Emre Göksan Pabuçcu Alper Kahraman İbrahim Yalçın Uğur Fırat Ortaç The Role of Human Papilloma Virus in Synchronous Gynecologic Malignancies: A Report of Two Cases and Review of the Literature Gynecology Obstetrics & Reproductive Medicine Cervical carcinoma Endometrial carcinoma Human papilloma virus Synchronous cancer |
| title | The Role of Human Papilloma Virus in Synchronous Gynecologic Malignancies: A Report of Two Cases and Review of the Literature |
| title_full | The Role of Human Papilloma Virus in Synchronous Gynecologic Malignancies: A Report of Two Cases and Review of the Literature |
| title_fullStr | The Role of Human Papilloma Virus in Synchronous Gynecologic Malignancies: A Report of Two Cases and Review of the Literature |
| title_full_unstemmed | The Role of Human Papilloma Virus in Synchronous Gynecologic Malignancies: A Report of Two Cases and Review of the Literature |
| title_short | The Role of Human Papilloma Virus in Synchronous Gynecologic Malignancies: A Report of Two Cases and Review of the Literature |
| title_sort | role of human papilloma virus in synchronous gynecologic malignancies a report of two cases and review of the literature |
| topic | Cervical carcinoma Endometrial carcinoma Human papilloma virus Synchronous cancer |
| url | https://gorm.com.tr/index.php/GORM/article/view/46 |
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