Improving CD3 bispecific antibody therapy in solid tumors using combination strategies

Improving CD3 bispecific antibody therapy in solid tumors using combination strategies

CD3 bispecific antibodies (bsAbs) are emerging as an important treatment option in the arsenal of oncologists. There are numerous FDA-approved CD3 bsAbs for both hematological and solid tumors. Despite these recent advances, the success of CD3 bsAbs in solid cancer has been hampered by hurdles like...

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Bibliographic Details
Main Authors: Katy Lloyd, Jim Middelburg, Vitalijs Ovcinnikovs, Nora Pencheva, Kristel Kemper, Thorbald van Hall
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Oncology
Subjects:
antibody
CD3
bispecific Ab
cancer
vaccination
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1548446/full
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