Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report

Cuicui Liu, Junyan Liu, Huiling Ren, Yuzhu Xu, Wanhu Liu Department of Neurology, The Third Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of ChinaCorrespondence: Wanhu Liu, Department of Neurology, The Third Hospital of Hebei Medical University, 139 Ziqiang Road, Shijiazhuang...

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Main Authors: Liu C, Liu J, Ren H, Xu Y, Liu W
Format: Article
Language:English
Published: Dove Medical Press 2025-02-01
Series:International Medical Case Reports Journal
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Online Access:https://www.dovepress.com/efficacy-of-intravenous-tenecteplase-bridge-thrombectomy-for-recurrent-peer-reviewed-fulltext-article-IMCRJ
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Summary:Cuicui Liu, Junyan Liu, Huiling Ren, Yuzhu Xu, Wanhu Liu Department of Neurology, The Third Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of ChinaCorrespondence: Wanhu Liu, Department of Neurology, The Third Hospital of Hebei Medical University, 139 Ziqiang Road, Shijiazhuang, 050000, People’s Republic of China, Email [email protected]: In the previous guideline recommendations, patients who have had a stroke within 3 months are excluded from intravenous thrombolysis (IVT) regimens. Some studies have suggested that IVT with alteplase (rt-PA) may be effective and safe in such patients, but evidence supporting the use of tenecteplase (TNK) is not sufficient. This paper includes an 80-year-old male patient readmitted for recurrence of ischaemic stroke (IS) after 48 days, who received TNK IVT as a bridging therapy prior to thrombectomy, with favourable results at 8-week follow-up. This case highlights that TNK alone or IVT as a bridging therapy prior to thrombectomy can also benefit patients with recurrent stroke within 3 months.Keywords: intravenous thrombolysis, recurrent ischemic stroke, tenecteplase
ISSN:1179-142X