Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report
Cuicui Liu, Junyan Liu, Huiling Ren, Yuzhu Xu, Wanhu Liu Department of Neurology, The Third Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of ChinaCorrespondence: Wanhu Liu, Department of Neurology, The Third Hospital of Hebei Medical University, 139 Ziqiang Road, Shijiazhuang...
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Dove Medical Press
2025-02-01
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| Series: | International Medical Case Reports Journal |
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| author | Liu C Liu J Ren H Xu Y Liu W |
| author_facet | Liu C Liu J Ren H Xu Y Liu W |
| author_sort | Liu C |
| collection | DOAJ |
| description | Cuicui Liu, Junyan Liu, Huiling Ren, Yuzhu Xu, Wanhu Liu Department of Neurology, The Third Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of ChinaCorrespondence: Wanhu Liu, Department of Neurology, The Third Hospital of Hebei Medical University, 139 Ziqiang Road, Shijiazhuang, 050000, People’s Republic of China, Email [email protected]: In the previous guideline recommendations, patients who have had a stroke within 3 months are excluded from intravenous thrombolysis (IVT) regimens. Some studies have suggested that IVT with alteplase (rt-PA) may be effective and safe in such patients, but evidence supporting the use of tenecteplase (TNK) is not sufficient. This paper includes an 80-year-old male patient readmitted for recurrence of ischaemic stroke (IS) after 48 days, who received TNK IVT as a bridging therapy prior to thrombectomy, with favourable results at 8-week follow-up. This case highlights that TNK alone or IVT as a bridging therapy prior to thrombectomy can also benefit patients with recurrent stroke within 3 months.Keywords: intravenous thrombolysis, recurrent ischemic stroke, tenecteplase |
| format | Article |
| id | doaj-art-72a9970f095040d0bd3ae177678ff035 |
| institution | Kabale University |
| issn | 1179-142X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj-art-72a9970f095040d0bd3ae177678ff0352025-02-11T17:30:56ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2025-02-01Volume 18235239100012Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case ReportLiu CLiu JRen HXu YLiu WCuicui Liu, Junyan Liu, Huiling Ren, Yuzhu Xu, Wanhu Liu Department of Neurology, The Third Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of ChinaCorrespondence: Wanhu Liu, Department of Neurology, The Third Hospital of Hebei Medical University, 139 Ziqiang Road, Shijiazhuang, 050000, People’s Republic of China, Email [email protected]: In the previous guideline recommendations, patients who have had a stroke within 3 months are excluded from intravenous thrombolysis (IVT) regimens. Some studies have suggested that IVT with alteplase (rt-PA) may be effective and safe in such patients, but evidence supporting the use of tenecteplase (TNK) is not sufficient. This paper includes an 80-year-old male patient readmitted for recurrence of ischaemic stroke (IS) after 48 days, who received TNK IVT as a bridging therapy prior to thrombectomy, with favourable results at 8-week follow-up. This case highlights that TNK alone or IVT as a bridging therapy prior to thrombectomy can also benefit patients with recurrent stroke within 3 months.Keywords: intravenous thrombolysis, recurrent ischemic stroke, tenecteplasehttps://www.dovepress.com/efficacy-of-intravenous-tenecteplase-bridge-thrombectomy-for-recurrent-peer-reviewed-fulltext-article-IMCRJintravenous thrombolysisrecurrent ischemic stroketenecteplase |
| spellingShingle | Liu C Liu J Ren H Xu Y Liu W Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report International Medical Case Reports Journal intravenous thrombolysis recurrent ischemic stroke tenecteplase |
| title | Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report |
| title_full | Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report |
| title_fullStr | Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report |
| title_full_unstemmed | Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report |
| title_short | Efficacy of Intravenous Tenecteplase Bridge Thrombectomy for Recurrent Ischemic Stroke Within 3 Months: A Case Report |
| title_sort | efficacy of intravenous tenecteplase bridge thrombectomy for recurrent ischemic stroke within 3 months a case report |
| topic | intravenous thrombolysis recurrent ischemic stroke tenecteplase |
| url | https://www.dovepress.com/efficacy-of-intravenous-tenecteplase-bridge-thrombectomy-for-recurrent-peer-reviewed-fulltext-article-IMCRJ |
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