Memories of a young student: the early days of splicing regulation with François Gros
I joined the laboratory of François Gros as a young student in the mid-1980s and worked on the characterization of the $\beta $-tropomyosin gene in chicken and the regulation of alternative splicing of its transcript, under the supervision of Marc Fiszman. In particular, I was interested in how seco...
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| Format: | Article |
| Language: | English |
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Académie des sciences
2024-01-01
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| Series: | Comptes Rendus Biologies |
| Subjects: | |
| Online Access: | https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.138/ |
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| Summary: | I joined the laboratory of François Gros as a young student in the mid-1980s and worked on the characterization of the $\beta $-tropomyosin gene in chicken and the regulation of alternative splicing of its transcript, under the supervision of Marc Fiszman. In particular, I was interested in how secondary structures of the RNA influence the recognition of exons specifically used in muscle cells. I will recall a few memories on how interacting with François on this project shaped my perception of the scientific process and of the relationships between models and data. Later I worked on many aspects of RNA biology, from transcription to mRNP biogenesis and non-coding RNAs. |
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| ISSN: | 1768-3238 |