Memories of a young student: the early days of splicing regulation with François Gros

I joined the laboratory of François Gros as a young student in the mid-1980s and worked on the characterization of the $\beta $-tropomyosin gene in chicken and the regulation of alternative splicing of its transcript, under the supervision of Marc Fiszman. In particular, I was interested in how seco...

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Main Author: Libri, Domenico
Format: Article
Language:English
Published: Académie des sciences 2024-01-01
Series:Comptes Rendus Biologies
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Online Access:https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.138/
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author Libri, Domenico
author_facet Libri, Domenico
author_sort Libri, Domenico
collection DOAJ
description I joined the laboratory of François Gros as a young student in the mid-1980s and worked on the characterization of the $\beta $-tropomyosin gene in chicken and the regulation of alternative splicing of its transcript, under the supervision of Marc Fiszman. In particular, I was interested in how secondary structures of the RNA influence the recognition of exons specifically used in muscle cells. I will recall a few memories on how interacting with François on this project shaped my perception of the scientific process and of the relationships between models and data. Later I worked on many aspects of RNA biology, from transcription to mRNP biogenesis and non-coding RNAs.
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institution Kabale University
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spelling doaj-art-7630c6233d2b422ebf18a42c8838f5ad2025-02-07T10:36:48ZengAcadémie des sciencesComptes Rendus Biologies1768-32382024-01-01346S2555710.5802/crbiol.13810.5802/crbiol.138Memories of a young student: the early days of splicing regulation with François GrosLibri, Domenico0https://orcid.org/0000-0001-6728-0594Institut de Génétique Moléculaire de Montpellier, Montpellier, FranceI joined the laboratory of François Gros as a young student in the mid-1980s and worked on the characterization of the $\beta $-tropomyosin gene in chicken and the regulation of alternative splicing of its transcript, under the supervision of Marc Fiszman. In particular, I was interested in how secondary structures of the RNA influence the recognition of exons specifically used in muscle cells. I will recall a few memories on how interacting with François on this project shaped my perception of the scientific process and of the relationships between models and data. Later I worked on many aspects of RNA biology, from transcription to mRNP biogenesis and non-coding RNAs.https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.138/MemoriesAlternative splicingMuscle differentiationHistory of muscle protein genes
spellingShingle Libri, Domenico
Memories of a young student: the early days of splicing regulation with François Gros
Comptes Rendus Biologies
Memories
Alternative splicing
Muscle differentiation
History of muscle protein genes
title Memories of a young student: the early days of splicing regulation with François Gros
title_full Memories of a young student: the early days of splicing regulation with François Gros
title_fullStr Memories of a young student: the early days of splicing regulation with François Gros
title_full_unstemmed Memories of a young student: the early days of splicing regulation with François Gros
title_short Memories of a young student: the early days of splicing regulation with François Gros
title_sort memories of a young student the early days of splicing regulation with francois gros
topic Memories
Alternative splicing
Muscle differentiation
History of muscle protein genes
url https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.138/
work_keys_str_mv AT libridomenico memoriesofayoungstudenttheearlydaysofsplicingregulationwithfrancoisgros