Modern options of application of domperidone in gastroenterology
The aim of review. To carry out analysis of the publications devoted to application of prokinetic drug domperidone (D) at various gastroenterological diseases.Key points. Literature data demonstrate, that dopamine receptor antagonist D is effective drug for treatment of such diseases, as functional...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2012-11-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1329 |
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| _version_ | 1823860204413911040 |
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| author | A. A. Sheptulin |
| author_facet | A. A. Sheptulin |
| author_sort | A. A. Sheptulin |
| collection | DOAJ |
| description | The aim of review. To carry out analysis of the publications devoted to application of prokinetic drug domperidone (D) at various gastroenterological diseases.Key points. Literature data demonstrate, that dopamine receptor antagonist D is effective drug for treatment of such diseases, as functional dyspepsia, diabetic and idiopathic gastroparesis, gastroesophageal reflux disease (within combined treatment modes), and for relief of nausea and vomiting, caused by cytotoxic agents as well. Side effects at application of D are determined by risk of hyperprolactinemia, which rarely clinically relevant.Conclusion. Domperidone can be successfully applied for treatment of gastroenterological diseases accompanying primary or secondary disorders of stomach and duodenum motility. |
| format | Article |
| id | doaj-art-7647fd1f4f9749c4ae53f609e233486c |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2012-11-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-7647fd1f4f9749c4ae53f609e233486c2025-02-10T16:14:32ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732012-11-0122648901Modern options of application of domperidone in gastroenterologyA. A. Sheptulin0ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздравсоцразвития РФThe aim of review. To carry out analysis of the publications devoted to application of prokinetic drug domperidone (D) at various gastroenterological diseases.Key points. Literature data demonstrate, that dopamine receptor antagonist D is effective drug for treatment of such diseases, as functional dyspepsia, diabetic and idiopathic gastroparesis, gastroesophageal reflux disease (within combined treatment modes), and for relief of nausea and vomiting, caused by cytotoxic agents as well. Side effects at application of D are determined by risk of hyperprolactinemia, which rarely clinically relevant.Conclusion. Domperidone can be successfully applied for treatment of gastroenterological diseases accompanying primary or secondary disorders of stomach and duodenum motility.https://www.gastro-j.ru/jour/article/view/1329disorders of motility of the stomach and duodenumprokineticsdomperidone |
| spellingShingle | A. A. Sheptulin Modern options of application of domperidone in gastroenterology Российский журнал гастроэнтерологии, гепатологии, колопроктологии disorders of motility of the stomach and duodenum prokinetics domperidone |
| title | Modern options of application of domperidone in gastroenterology |
| title_full | Modern options of application of domperidone in gastroenterology |
| title_fullStr | Modern options of application of domperidone in gastroenterology |
| title_full_unstemmed | Modern options of application of domperidone in gastroenterology |
| title_short | Modern options of application of domperidone in gastroenterology |
| title_sort | modern options of application of domperidone in gastroenterology |
| topic | disorders of motility of the stomach and duodenum prokinetics domperidone |
| url | https://www.gastro-j.ru/jour/article/view/1329 |
| work_keys_str_mv | AT aasheptulin modernoptionsofapplicationofdomperidoneingastroenterology |