State of the art progress of Evolvulus alsinoides in pharmacological activity and plant tissue culture: A potent Chinese medicinal plant
Introduction: Evolvulus alsinoides (Convolvulaceae family), commonly known as ‘tu ding gui’ in Chinese. It is a medicinal plant with strong roots in traditional Chinese medicine (TCM). Its rich secondary metabolite compositions, as well as therapeutic and medical properties, yet it has limited resea...
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Elsevier
2025-03-01
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| Series: | Pharmacological Research - Modern Chinese Medicine |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667142525000156 |
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| author | Collince Omondi Awere Valentine Chikaodili Anadebe Rakkammal Kasinathan Pandiyan Muthuramalingam Ramesh Manikandan |
| author_facet | Collince Omondi Awere Valentine Chikaodili Anadebe Rakkammal Kasinathan Pandiyan Muthuramalingam Ramesh Manikandan |
| author_sort | Collince Omondi Awere |
| collection | DOAJ |
| description | Introduction: Evolvulus alsinoides (Convolvulaceae family), commonly known as ‘tu ding gui’ in Chinese. It is a medicinal plant with strong roots in traditional Chinese medicine (TCM). Its rich secondary metabolite compositions, as well as therapeutic and medical properties, yet it has limited research. This has prompted scientific investigation into its potential pharmacological benefits and bridging the gap between conventional medicine and contemporary therapeutic advancements in pharmacological research. Methods: A total of 60 papers were identified through internet databases such as Scopus, Google Scholar, Web of Science, and PubMed. Various keywords such as E. alsinoides micropropagation, phytochemistry, and pharmacology were utilized to search for information. This review extensively analyzes the applications of E. alsinoides, including extraction and quantification methodologies, secondary metabolites, and pharmacological activities. Results: E. alsinoides contain an abundance of secondary metabolites, such as triterpenoids, flavonoids, terpenoids, alkaloids, and essential oils, which contribute to its anti-inflammatory, antimicrobial, antioxidant, antiproliferative, and immunomodulatory properties. The existence of these bioactive chemicals is consistent with their historic usage in treating a variety of illnesses and neurological conditions. Discussion: E. alsinoides has enormous therapeutic potential beyond its traditional usage in Chinese medicine. The diverse medicinal profile shows that it has the potential to treat a variety of health issues. Nevertheless, thorough clinical trials and translational research are required to bridge the gap between conventional knowledge and current medical uses. This study provides a touchstone to integrate current information and identify areas for future research on E. alsinoides as a multifunctional plant, with applications in pharmacology and beyond. |
| format | Article |
| id | doaj-art-7833f1fac91c4d8e94f818bbff9761e8 |
| institution | Kabale University |
| issn | 2667-1425 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pharmacological Research - Modern Chinese Medicine |
| spelling | doaj-art-7833f1fac91c4d8e94f818bbff9761e82025-02-11T04:35:34ZengElsevierPharmacological Research - Modern Chinese Medicine2667-14252025-03-0114100586State of the art progress of Evolvulus alsinoides in pharmacological activity and plant tissue culture: A potent Chinese medicinal plantCollince Omondi Awere0Valentine Chikaodili Anadebe1Rakkammal Kasinathan2Pandiyan Muthuramalingam3Ramesh Manikandan4Department of Biotechnology, Science Campus, Alagappa University, Karaikudi 630003, IndiaDepartment of Chemical Engineering, Alex Ekwueme Federal University Ndufu Alike, PMB 1010, Abakaliki, Ebonyi State, NigeriaDepartment of Biotechnology, Science Campus, Alagappa University, Karaikudi 630003, IndiaDivision of Horticultural Science, College of Agriculture and Life Sciences, Gyeongsang National University, Jinju, 52725, South KoreaDepartment of Biotechnology, Science Campus, Alagappa University, Karaikudi 630003, India; Corresponding author.Introduction: Evolvulus alsinoides (Convolvulaceae family), commonly known as ‘tu ding gui’ in Chinese. It is a medicinal plant with strong roots in traditional Chinese medicine (TCM). Its rich secondary metabolite compositions, as well as therapeutic and medical properties, yet it has limited research. This has prompted scientific investigation into its potential pharmacological benefits and bridging the gap between conventional medicine and contemporary therapeutic advancements in pharmacological research. Methods: A total of 60 papers were identified through internet databases such as Scopus, Google Scholar, Web of Science, and PubMed. Various keywords such as E. alsinoides micropropagation, phytochemistry, and pharmacology were utilized to search for information. This review extensively analyzes the applications of E. alsinoides, including extraction and quantification methodologies, secondary metabolites, and pharmacological activities. Results: E. alsinoides contain an abundance of secondary metabolites, such as triterpenoids, flavonoids, terpenoids, alkaloids, and essential oils, which contribute to its anti-inflammatory, antimicrobial, antioxidant, antiproliferative, and immunomodulatory properties. The existence of these bioactive chemicals is consistent with their historic usage in treating a variety of illnesses and neurological conditions. Discussion: E. alsinoides has enormous therapeutic potential beyond its traditional usage in Chinese medicine. The diverse medicinal profile shows that it has the potential to treat a variety of health issues. Nevertheless, thorough clinical trials and translational research are required to bridge the gap between conventional knowledge and current medical uses. This study provides a touchstone to integrate current information and identify areas for future research on E. alsinoides as a multifunctional plant, with applications in pharmacology and beyond.http://www.sciencedirect.com/science/article/pii/S2667142525000156Evolvulus alsinoidesAntiproliferativePharmacologySecondary metabolitesChinese medicine |
| spellingShingle | Collince Omondi Awere Valentine Chikaodili Anadebe Rakkammal Kasinathan Pandiyan Muthuramalingam Ramesh Manikandan State of the art progress of Evolvulus alsinoides in pharmacological activity and plant tissue culture: A potent Chinese medicinal plant Pharmacological Research - Modern Chinese Medicine Evolvulus alsinoides Antiproliferative Pharmacology Secondary metabolites Chinese medicine |
| title | State of the art progress of Evolvulus alsinoides in pharmacological activity and plant tissue culture: A potent Chinese medicinal plant |
| title_full | State of the art progress of Evolvulus alsinoides in pharmacological activity and plant tissue culture: A potent Chinese medicinal plant |
| title_fullStr | State of the art progress of Evolvulus alsinoides in pharmacological activity and plant tissue culture: A potent Chinese medicinal plant |
| title_full_unstemmed | State of the art progress of Evolvulus alsinoides in pharmacological activity and plant tissue culture: A potent Chinese medicinal plant |
| title_short | State of the art progress of Evolvulus alsinoides in pharmacological activity and plant tissue culture: A potent Chinese medicinal plant |
| title_sort | state of the art progress of evolvulus alsinoides in pharmacological activity and plant tissue culture a potent chinese medicinal plant |
| topic | Evolvulus alsinoides Antiproliferative Pharmacology Secondary metabolites Chinese medicine |
| url | http://www.sciencedirect.com/science/article/pii/S2667142525000156 |
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