PLGA scaffold combined with MSCs transplantation improved neural function and brain tissue structure in rats with traumatic brain injury

PLGA scaffold combined with MSCs transplantation improved neural function and brain tissue structure in rats with traumatic brain injury

Poly (lactic-co-glycolic acid) (PLGA) is an important biomaterial for tissue defect repair, but its application in replacing missing brain tissue needs improvement. Mesenchymal stem cells (MSCs) have been used to treat various neurological diseases, but they face challenges when filling large tissue...

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Bibliographic Details
Main Authors: Na Xu, Zihuan Sun, Weikang Guan, Yiming Liu, Yun Gao, Chaoxian Yang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Brain Research Bulletin
Subjects:
Traumatic brain injury
Poly (lactic-co-glycolic acid)
Mesenchymal stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025000280
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