Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana
BackgroundMale infertility is a significant global public health issue, with modifiable lifestyle factors such as smoking, obesity, and psychological stress contributing to impaired semen quality and hormonal dysregulation. This study investigates the relationships between modifiable lifestyle facto...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-02-01
|
| Series: | Frontiers in Reproductive Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/frph.2025.1520938/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823859258105528320 |
|---|---|
| author | Brodrick Yeboah Amoah Saliah Yao Bayamina Cosmos Gborsong Hubert Owusu George Awuku Asare Emmanuel Kwabena Yeboah Josephine Ablakwa Georgina Hammond |
| author_facet | Brodrick Yeboah Amoah Saliah Yao Bayamina Cosmos Gborsong Hubert Owusu George Awuku Asare Emmanuel Kwabena Yeboah Josephine Ablakwa Georgina Hammond |
| author_sort | Brodrick Yeboah Amoah |
| collection | DOAJ |
| description | BackgroundMale infertility is a significant global public health issue, with modifiable lifestyle factors such as smoking, obesity, and psychological stress contributing to impaired semen quality and hormonal dysregulation. This study investigates the relationships between modifiable lifestyle factors, reproductive hormones, and semen quality in Ghanaian males attending an IVF clinic.MethodsA cross-sectional study was conducted with 212 male participants recruited from a fertility clinic in Ghana. Lifestyle factors were assessed using standardized questionnaires, and semen samples were analyzed following WHO guidelines. Hormonal profiles (LH, FSH, testosterone, estradiol) were measured using the enzyme-linked fluorescent assay (ELFA). Statistical analyses included Pearson's product-moment correlation and Bonferroni correction.ResultsSmoking and psychological stress were significantly associated with reduced sperm motility, viability, and concentration (p < 0.05). Elevated BMI correlated negatively with sperm concentration and testosterone levels (p < 0.05). Alcoholic bitters was linked to decreased semen quality, while caffeine consumption showed a positive association with progressive sperm motility.ConclusionModifiable lifestyle factors, such as smoking, psychological stress, and increased body mass index (BMI), play a crucial role in male reproductive health by adversely affecting semen parameters and hormonal balance. These findings emphasize the need for public health interventions targeting modifiable behaviors to improve fertility outcomes. |
| format | Article |
| id | doaj-art-7a0f98ddc531493d9e6147384f5080f0 |
| institution | Kabale University |
| issn | 2673-3153 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Reproductive Health |
| spelling | doaj-art-7a0f98ddc531493d9e6147384f5080f02025-02-11T06:59:06ZengFrontiers Media S.A.Frontiers in Reproductive Health2673-31532025-02-01710.3389/frph.2025.15209381520938Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in GhanaBrodrick Yeboah Amoah0Saliah Yao Bayamina1Cosmos Gborsong2Hubert Owusu3George Awuku Asare4Emmanuel Kwabena Yeboah5Josephine Ablakwa6Georgina Hammond7Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra, GhanaDepartment of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra, GhanaDepartment of Molecular Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, GhanaDepartment of Molecular Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, GhanaDepartment of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra, GhanaDepartment of Medical Sciences, Royal Melbourne Institute of Technology, Melbourne, VIC, AustraliaDepartment of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Accra, GhanaDepartment of Anatomy and Physiology, Institute for Cardiovascular Prevention, IPEK, University of Munich, Munich, GermanyBackgroundMale infertility is a significant global public health issue, with modifiable lifestyle factors such as smoking, obesity, and psychological stress contributing to impaired semen quality and hormonal dysregulation. This study investigates the relationships between modifiable lifestyle factors, reproductive hormones, and semen quality in Ghanaian males attending an IVF clinic.MethodsA cross-sectional study was conducted with 212 male participants recruited from a fertility clinic in Ghana. Lifestyle factors were assessed using standardized questionnaires, and semen samples were analyzed following WHO guidelines. Hormonal profiles (LH, FSH, testosterone, estradiol) were measured using the enzyme-linked fluorescent assay (ELFA). Statistical analyses included Pearson's product-moment correlation and Bonferroni correction.ResultsSmoking and psychological stress were significantly associated with reduced sperm motility, viability, and concentration (p < 0.05). Elevated BMI correlated negatively with sperm concentration and testosterone levels (p < 0.05). Alcoholic bitters was linked to decreased semen quality, while caffeine consumption showed a positive association with progressive sperm motility.ConclusionModifiable lifestyle factors, such as smoking, psychological stress, and increased body mass index (BMI), play a crucial role in male reproductive health by adversely affecting semen parameters and hormonal balance. These findings emphasize the need for public health interventions targeting modifiable behaviors to improve fertility outcomes.https://www.frontiersin.org/articles/10.3389/frph.2025.1520938/fullsemen qualitylifestyle factorsmale infertilityreproductive hormonesIVFGhana |
| spellingShingle | Brodrick Yeboah Amoah Saliah Yao Bayamina Cosmos Gborsong Hubert Owusu George Awuku Asare Emmanuel Kwabena Yeboah Josephine Ablakwa Georgina Hammond Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana Frontiers in Reproductive Health semen quality lifestyle factors male infertility reproductive hormones IVF Ghana |
| title | Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana |
| title_full | Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana |
| title_fullStr | Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana |
| title_full_unstemmed | Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana |
| title_short | Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana |
| title_sort | modifiable life style factors and male reproductive health a cross sectional study in ivf clinic attendees in ghana |
| topic | semen quality lifestyle factors male infertility reproductive hormones IVF Ghana |
| url | https://www.frontiersin.org/articles/10.3389/frph.2025.1520938/full |
| work_keys_str_mv | AT brodrickyeboahamoah modifiablelifestylefactorsandmalereproductivehealthacrosssectionalstudyinivfclinicattendeesinghana AT saliahyaobayamina modifiablelifestylefactorsandmalereproductivehealthacrosssectionalstudyinivfclinicattendeesinghana AT cosmosgborsong modifiablelifestylefactorsandmalereproductivehealthacrosssectionalstudyinivfclinicattendeesinghana AT hubertowusu modifiablelifestylefactorsandmalereproductivehealthacrosssectionalstudyinivfclinicattendeesinghana AT georgeawukuasare modifiablelifestylefactorsandmalereproductivehealthacrosssectionalstudyinivfclinicattendeesinghana AT emmanuelkwabenayeboah modifiablelifestylefactorsandmalereproductivehealthacrosssectionalstudyinivfclinicattendeesinghana AT josephineablakwa modifiablelifestylefactorsandmalereproductivehealthacrosssectionalstudyinivfclinicattendeesinghana AT georginahammond modifiablelifestylefactorsandmalereproductivehealthacrosssectionalstudyinivfclinicattendeesinghana |