Black tongue caused by linezolid in children: One case report and literature review

Linezolid is commonly used to treat multidrug-resistant Gram-positive bacterial infections. Among children, the most common adverse reactions associated with linezolid administration encompass diarrhoea, vomiting, headache and thrombocytopenia. It is noted that tongue discoloration can occur with li...

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Main Authors: Chunyu Zhang, Hongxia Shen, Jing Zhang, Lujie Xu, Meixing Yan, Chang Liu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:IDCases
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214250925000368
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author Chunyu Zhang
Hongxia Shen
Jing Zhang
Lujie Xu
Meixing Yan
Chang Liu
author_facet Chunyu Zhang
Hongxia Shen
Jing Zhang
Lujie Xu
Meixing Yan
Chang Liu
author_sort Chunyu Zhang
collection DOAJ
description Linezolid is commonly used to treat multidrug-resistant Gram-positive bacterial infections. Among children, the most common adverse reactions associated with linezolid administration encompass diarrhoea, vomiting, headache and thrombocytopenia. It is noted that tongue discoloration can occur with linezolid in the medication package insert. In this article, we present a case of a child with black tongue as a rare adverse reaction to linezolid and review of relevant literature.
format Article
id doaj-art-7a97a4085c584f138f3c4a523d7800ef
institution Kabale University
issn 2214-2509
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series IDCases
spelling doaj-art-7a97a4085c584f138f3c4a523d7800ef2025-02-07T04:47:32ZengElsevierIDCases2214-25092025-01-0139e02181Black tongue caused by linezolid in children: One case report and literature reviewChunyu Zhang0Hongxia Shen1Jing Zhang2Lujie Xu3Meixing Yan4Chang Liu5Department of Pharmacy, Dongming People's Hospital, Dongming, Shandong Province 274500, ChinaDepartment of Pharmacy, Qingdao Women and Children’s Hospital, Qingdao, Shandong 266000, ChinaDepartment of Pharmacy, Dongming People's Hospital, Dongming, Shandong Province 274500, ChinaDepartment of Pharmacy, Qingdao Women and Children’s Hospital, Qingdao, Shandong 266000, ChinaDepartment of Pharmacy, Qingdao Women and Children’s Hospital, Qingdao, Shandong 266000, ChinaDepartment of Pharmacy, Qingdao Women and Children’s Hospital, Qingdao, Shandong 266000, China; Corresponding author.Linezolid is commonly used to treat multidrug-resistant Gram-positive bacterial infections. Among children, the most common adverse reactions associated with linezolid administration encompass diarrhoea, vomiting, headache and thrombocytopenia. It is noted that tongue discoloration can occur with linezolid in the medication package insert. In this article, we present a case of a child with black tongue as a rare adverse reaction to linezolid and review of relevant literature.http://www.sciencedirect.com/science/article/pii/S2214250925000368Back tongueLinezolidChildrenMedicineAntibacterial drugAdverse reaction
spellingShingle Chunyu Zhang
Hongxia Shen
Jing Zhang
Lujie Xu
Meixing Yan
Chang Liu
Black tongue caused by linezolid in children: One case report and literature review
IDCases
Back tongue
Linezolid
Children
Medicine
Antibacterial drug
Adverse reaction
title Black tongue caused by linezolid in children: One case report and literature review
title_full Black tongue caused by linezolid in children: One case report and literature review
title_fullStr Black tongue caused by linezolid in children: One case report and literature review
title_full_unstemmed Black tongue caused by linezolid in children: One case report and literature review
title_short Black tongue caused by linezolid in children: One case report and literature review
title_sort black tongue caused by linezolid in children one case report and literature review
topic Back tongue
Linezolid
Children
Medicine
Antibacterial drug
Adverse reaction
url http://www.sciencedirect.com/science/article/pii/S2214250925000368
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AT jingzhang blacktonguecausedbylinezolidinchildrenonecasereportandliteraturereview
AT lujiexu blacktonguecausedbylinezolidinchildrenonecasereportandliteraturereview
AT meixingyan blacktonguecausedbylinezolidinchildrenonecasereportandliteraturereview
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