Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort study
BackgroundThis study explores the longitudinal relationship between the Weight-Adjusted Waist Index (WWI), an innovative obesity metric, and stroke incidence in aged 45 and older Chinese adults.MethodsData from 9,725 individuals aged 45 years and older were analyzed from the China Health and Retirem...
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Frontiers Media S.A.
2025-02-01
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Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1505364/full |
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author | Xiaoqiang Li Xiangmao Zhou Hui Du Hui Wang Zhijian Tan Yaqing Zeng Zhibin Song Guifeng Zhang |
author_facet | Xiaoqiang Li Xiangmao Zhou Hui Du Hui Wang Zhijian Tan Yaqing Zeng Zhibin Song Guifeng Zhang |
author_sort | Xiaoqiang Li |
collection | DOAJ |
description | BackgroundThis study explores the longitudinal relationship between the Weight-Adjusted Waist Index (WWI), an innovative obesity metric, and stroke incidence in aged 45 and older Chinese adults.MethodsData from 9,725 individuals aged 45 years and older were analyzed from the China Health and Retirement Longitudinal Study (2011–2020). Baseline characteristics were analyzed across different quartiles of the WWI. Stroke incidents were determined through self-reported doctor diagnoses. Multivariate logistic regression analyses and curve fitting assessed the WWI-stroke risk relationship, adjusting for various demographic, lifestyle, and health-related factors.ResultsHigher WWI quartiles were associated with older age and higher prevalence of stroke and adverse health conditions. In the fully adjusted model, participants in the highest WWI quartile had an odds ratio of 1.52 (95% CI: 1.19, 1.92) for stroke compared to the lowest quartile. Curve fitting revealed a linear relationship between WWI and stroke risk, consistent across various demographic and clinical subgroups.ConclusionHigher WWI is linked to an increased risk of stroke in aged 45 and older Chinese adults over an eight-year period. WWI may serve as an effective tool for predicting long-term stroke risk within this population. However, the study is limited by the reliance on self-reported stroke diagnoses and the presence of potential residual confounding factors. |
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institution | Kabale University |
issn | 2296-2565 |
language | English |
publishDate | 2025-02-01 |
publisher | Frontiers Media S.A. |
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series | Frontiers in Public Health |
spelling | doaj-art-7c9231360e6c46838fa88bdddff711362025-02-12T07:26:24ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-02-011310.3389/fpubh.2025.15053641505364Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort studyXiaoqiang Li0Xiangmao Zhou1Hui Du2Hui Wang3Zhijian Tan4Yaqing Zeng5Zhibin Song6Guifeng Zhang7Department of Neurology, Xiaolan People’s Hospital of Zhongshan (The Fifth People’s Hospital of ZhongShan), Guangdong, ChinaDepartment of Gastrointestinal Surgery, The Central Hospital of Yongzhou, Yongzhou, Hunan, ChinaDepartment of Blood Transfusion, Xiaolan People’s Hospital of Zhongshan (The Fifth People’s Hospital of ZhongShan), Guangdong, ChinaDepartment of Neurology, Xiaolan People’s Hospital of Zhongshan (The Fifth People’s Hospital of ZhongShan), Guangdong, ChinaDepartment of Neurology, Xiaolan People’s Hospital of Zhongshan (The Fifth People’s Hospital of ZhongShan), Guangdong, ChinaDepartment of Neurology, Xiaolan People’s Hospital of Zhongshan (The Fifth People’s Hospital of ZhongShan), Guangdong, ChinaDepartment of Neurology, Xiaolan People’s Hospital of Zhongshan (The Fifth People’s Hospital of ZhongShan), Guangdong, ChinaDepartment of Neurology, Xiaolan People’s Hospital of Zhongshan (The Fifth People’s Hospital of ZhongShan), Guangdong, ChinaBackgroundThis study explores the longitudinal relationship between the Weight-Adjusted Waist Index (WWI), an innovative obesity metric, and stroke incidence in aged 45 and older Chinese adults.MethodsData from 9,725 individuals aged 45 years and older were analyzed from the China Health and Retirement Longitudinal Study (2011–2020). Baseline characteristics were analyzed across different quartiles of the WWI. Stroke incidents were determined through self-reported doctor diagnoses. Multivariate logistic regression analyses and curve fitting assessed the WWI-stroke risk relationship, adjusting for various demographic, lifestyle, and health-related factors.ResultsHigher WWI quartiles were associated with older age and higher prevalence of stroke and adverse health conditions. In the fully adjusted model, participants in the highest WWI quartile had an odds ratio of 1.52 (95% CI: 1.19, 1.92) for stroke compared to the lowest quartile. Curve fitting revealed a linear relationship between WWI and stroke risk, consistent across various demographic and clinical subgroups.ConclusionHigher WWI is linked to an increased risk of stroke in aged 45 and older Chinese adults over an eight-year period. WWI may serve as an effective tool for predicting long-term stroke risk within this population. However, the study is limited by the reliance on self-reported stroke diagnoses and the presence of potential residual confounding factors.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1505364/fullWeight-Adjusted Waist IndexobesitystrokeCHARLSChina adults |
spellingShingle | Xiaoqiang Li Xiangmao Zhou Hui Du Hui Wang Zhijian Tan Yaqing Zeng Zhibin Song Guifeng Zhang Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort study Frontiers in Public Health Weight-Adjusted Waist Index obesity stroke CHARLS China adults |
title | Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort study |
title_full | Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort study |
title_fullStr | Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort study |
title_full_unstemmed | Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort study |
title_short | Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort study |
title_sort | longitudinal relationship between baseline weight adjusted waist index and stroke risk over 8 years in chinese adults aged 45 and older a prospective cohort study |
topic | Weight-Adjusted Waist Index obesity stroke CHARLS China adults |
url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1505364/full |
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