Safety profiles of IDH inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database

Safety profiles of IDH inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database

Abstract Background With the increased use of isocitrate dehydrogenase (IDH) inhibitors in acute myeloid leukemia (AML) and cholangiocarcinoma, the toxicity of these drugs is a growing concern. This study aimed to evaluate the adverse events (AEs) of IDH inhibitors based on the Food and Drug Adminis...

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Bibliographic Details
Main Authors: Ximu Sun, Han Zhou, Yanming Li, Yanhui Luo, Qixiang Guo, Yixin Sun, Chenguang Jia, Bin Wang, Maoquan Qin, Peng Guo
Format: Article
Language:English
Published: SpringerOpen 2025-02-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
IDH inhibitors
Enasidenib
Ivosidenib
Olutasidenib
FAERS
Pharmacovigilance
Online Access:https://doi.org/10.1186/s43094-025-00769-8
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https://doi.org/10.1186/s43094-025-00769-8

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