Effect of Low Dose Aspirin in Low Risk Pregnant Ladies with Abnormal Uterine Artery Doppler Results, and the Evaluation of Maternal and Fetal outcomes: A Randomized Clinical Trial

This study aimed to identify the effect of low dose aspirin administration in low risk pregnant ladies who have abnormal uterine artery Doppler results. Patients and Methods: A randomized clinical trial was performed on 50 pregnant ladies (?16 weeks of gestation) in Sulaymaniyah Maternity Teaching H...

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Main Authors: Parzhin Jalal Ali, Chro Najmaddin Fattah
Format: Article
Language:English
Published: Sulaimani Polytechnic University 2018-07-01
Series:Kurdistan Journal of Applied Research
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Online Access:https://www.kjar.spu.edu.iq/index.php/kjar/article/view/202
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author Parzhin Jalal Ali
Chro Najmaddin Fattah
author_facet Parzhin Jalal Ali
Chro Najmaddin Fattah
author_sort Parzhin Jalal Ali
collection DOAJ
description This study aimed to identify the effect of low dose aspirin administration in low risk pregnant ladies who have abnormal uterine artery Doppler results. Patients and Methods: A randomized clinical trial was performed on 50 pregnant ladies (?16 weeks of gestation) in Sulaymaniyah Maternity Teaching Hospital during January 2017 to January 2018. The participants were randomly enrolled into two groups; the participants in the first group were given 100 mg of aspirin tablet each but the other group was given nothing. Results: Preeclampsia was significantly (P-value of <0.001) less in the aspirin group as compared to the other group (16% and 40% respectively). The pulsatility index (PI) was not significantly different in both the groups (P-value = 0.69), but resistance index (RI) was significantly lower in the aspirin group (P-value of <0.001). Conclusion: Doppler study of the uterine artery at 16 weeks or higher in low risk pregnant women appears to be useful as a screening test and low dose of aspirin therapy at early stage of pregnancy will decrease the incidence of preeclampsia.  
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spelling doaj-art-84e94f45a35d4769af5a36c3ba9c42942025-02-11T21:01:28ZengSulaimani Polytechnic UniversityKurdistan Journal of Applied Research2411-76842411-77062018-07-013210.24017/science.2018.2.14Effect of Low Dose Aspirin in Low Risk Pregnant Ladies with Abnormal Uterine Artery Doppler Results, and the Evaluation of Maternal and Fetal outcomes: A Randomized Clinical TrialParzhin Jalal Ali0Chro Najmaddin Fattah1Obstetrics and Gynecology Department, Sulaimani Maternity Teaching Hospital, Sulaimani, IraqObstetrics and Gynecology Department, School of Medicine/University of Sulaimani, Sulaymaniyah, IraqThis study aimed to identify the effect of low dose aspirin administration in low risk pregnant ladies who have abnormal uterine artery Doppler results. Patients and Methods: A randomized clinical trial was performed on 50 pregnant ladies (?16 weeks of gestation) in Sulaymaniyah Maternity Teaching Hospital during January 2017 to January 2018. The participants were randomly enrolled into two groups; the participants in the first group were given 100 mg of aspirin tablet each but the other group was given nothing. Results: Preeclampsia was significantly (P-value of <0.001) less in the aspirin group as compared to the other group (16% and 40% respectively). The pulsatility index (PI) was not significantly different in both the groups (P-value = 0.69), but resistance index (RI) was significantly lower in the aspirin group (P-value of <0.001). Conclusion: Doppler study of the uterine artery at 16 weeks or higher in low risk pregnant women appears to be useful as a screening test and low dose of aspirin therapy at early stage of pregnancy will decrease the incidence of preeclampsia.   https://www.kjar.spu.edu.iq/index.php/kjar/article/view/202Aspirin, Doppler ultrasonography, Low risk pregnancy, Preeclampsia, Pulsatility index (PI), Resistance index (RI).
spellingShingle Parzhin Jalal Ali
Chro Najmaddin Fattah
Effect of Low Dose Aspirin in Low Risk Pregnant Ladies with Abnormal Uterine Artery Doppler Results, and the Evaluation of Maternal and Fetal outcomes: A Randomized Clinical Trial
Kurdistan Journal of Applied Research
Aspirin, Doppler ultrasonography, Low risk pregnancy, Preeclampsia, Pulsatility index (PI), Resistance index (RI).
title Effect of Low Dose Aspirin in Low Risk Pregnant Ladies with Abnormal Uterine Artery Doppler Results, and the Evaluation of Maternal and Fetal outcomes: A Randomized Clinical Trial
title_full Effect of Low Dose Aspirin in Low Risk Pregnant Ladies with Abnormal Uterine Artery Doppler Results, and the Evaluation of Maternal and Fetal outcomes: A Randomized Clinical Trial
title_fullStr Effect of Low Dose Aspirin in Low Risk Pregnant Ladies with Abnormal Uterine Artery Doppler Results, and the Evaluation of Maternal and Fetal outcomes: A Randomized Clinical Trial
title_full_unstemmed Effect of Low Dose Aspirin in Low Risk Pregnant Ladies with Abnormal Uterine Artery Doppler Results, and the Evaluation of Maternal and Fetal outcomes: A Randomized Clinical Trial
title_short Effect of Low Dose Aspirin in Low Risk Pregnant Ladies with Abnormal Uterine Artery Doppler Results, and the Evaluation of Maternal and Fetal outcomes: A Randomized Clinical Trial
title_sort effect of low dose aspirin in low risk pregnant ladies with abnormal uterine artery doppler results and the evaluation of maternal and fetal outcomes a randomized clinical trial
topic Aspirin, Doppler ultrasonography, Low risk pregnancy, Preeclampsia, Pulsatility index (PI), Resistance index (RI).
url https://www.kjar.spu.edu.iq/index.php/kjar/article/view/202
work_keys_str_mv AT parzhinjalalali effectoflowdoseaspirininlowriskpregnantladieswithabnormaluterinearterydopplerresultsandtheevaluationofmaternalandfetaloutcomesarandomizedclinicaltrial
AT chronajmaddinfattah effectoflowdoseaspirininlowriskpregnantladieswithabnormaluterinearterydopplerresultsandtheevaluationofmaternalandfetaloutcomesarandomizedclinicaltrial