Effects of pesticide dichlorvos on liver injury in rats and related toxicity mechanisms

Effects of pesticide dichlorvos on liver injury in rats and related toxicity mechanisms

Dichlorvos (DDVP) is an organophosphorus pesticide commonly utilized in agricultural production. Recent epidemiological studies suggest that exposure to DDVP correlates with an increased incidence of liver disease. However, data regarding the hepatotoxicity of DDVP remain limited. Additionally, the...

Full description

Saved in:

Bibliographic Details
Main Authors:	Pengcheng Zhang, Zixian Zhou, Jiaqi Yao, Yuhong Jiang, Hang Lei, Zhijun Xie, Juan Li, Xianlin Zhao, Lv Zhu, Meihua Wan, Ling Liu, Wenfu Tang
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Series:	Ecotoxicology and Environmental Safety
Subjects:	Dichlorvos Liver damage IRGM Incomplete autophagy Apoptosis Ferroptosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651325000831
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Hesperidoside abolishes dichlorvos-mediated neurotoxicity in rats by suppressing oxidative stress, acetylcholinesterase inhibition, and NF-κB-p65/p53/caspase-3-mediated apoptosis
by: Adio J. Akamo, et al.
Published: (2025-02-01)

Transcriptome Analysis of Effect of Cordyceps militaris Aqueous Extract in Human Gastric Cancer Cell BGC-823 on Different RCD Pathways
by: Mingqi CUI, et al.
Published: (2025-02-01)

Metformin-induced mitophagy suppresses auditory hair cell apoptosis via AMPK pathway
by: Yifan Lai, et al.
Published: (2025-02-01)

Unravelling a mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in Mucopolysaccharidosis VII
by: Nishan Mandal, et al.
Published: (2025-03-01)

Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis
by: Jiaqi Yao, et al.
Published: (2025-02-01)

Some New Results for the $\mathscr{M}$-Transform Involving the Incomplete $I$-Functions
by: Sanjay Bhatter, et al.
Published: (2024-03-01)

Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc−/GSH/GPX4 axis
by: Fang-fang Yu, et al.
Published: (2025-01-01)

Improving ferroptosis-mediated immunotherapy for colorectal cancer through lysosome-targeted photodynamic therapy
by: Zhian Chen, et al.
Published: (2025-04-01)

Metformin exerted tumoricidal effects on colon cancer tumoroids via the regulation of autophagy pathway
by: Roya Shabkhizan, et al.
Published: (2025-02-01)

Cancer stem cells in head and neck squamous cell carcinoma and its associated markers: A review
by: Lavanya Mallika, et al.
Published: (2024-04-01)

Role of autophagy defects and significance of adherent-invasive <i>Escherichia coli</i> in Crohn's disease development
by: I. V. Mayev, et al.
Published: (2015-07-01)

Cybertoxicology, molecular docking, and experimental verification reveal the mechanism of action of chlorpyrifos on skin damage
by: Weibin Du, et al.
Published: (2025-01-01)

The ameliorative effects of melatonin against BDE-47-induced hippocampal neuronal ferroptosis and cognitive dysfunction through Nrf2-Chaperone-mediated autophagy of ACSL4 degradation
by: Quan Yuan, et al.
Published: (2025-01-01)

Immune-mediated mechanisms in acute osteofascial compartment syndrome: insights from multi-omics analysis
by: Qinzhen Lu, et al.
Published: (2025-02-01)

Plasma-derived extracellular vesicles prime alveolar macrophages for autophagy and ferroptosis in sepsis-induced acute lung injury
by: Rongzong Ye, et al.
Published: (2025-02-01)

Increased miRNA-375 causes oxidative damage but promotes apoptosis resistance and cell migration in the clam Ruditapes philippinarum
by: Ming Cong, et al.
Published: (2025-02-01)

Long-chain chlorinated paraffins (LCCPs) exposure induces apoptosis in primary chicken embryo hepatocytes through oxidative stress
by: Haochu Deng, et al.
Published: (2025-01-01)

Diisooctyl phthalate (DIOP) exposure leads to cell apoptosis to HUVEC cells and toxicity to Caenorhabditis elegans through increasing the oxidative stress
by: Siyuan Luo, et al.
Published: (2025-01-01)

Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription
by: Lipeng Pei, et al.
Published: (2025-02-01)

Autophagy is involved in the toxicity of the biocontrol agent GC16 against Tetranychus pueraricola (Acari: Tetranychidae) based on transcriptomic and proteomic analyses
by: Yanyan He, et al.
Published: (2025-02-01)

Assessment of the Effects of Chemotherapy on Ovarian Reserve in Rats
by: Ahmet Mete Ergenoğlu, et al.
Published: (2014-04-01)

Synergistic effects of PS-NPs and Cd on ovarian toxicity in adolescent rats: Ferroptosis by induction of mitochondrial redox imbalance via the SIRT3-SOD2/Gpx4 pathway
by: Hua Wu, et al.
Published: (2025-01-01)

Oxidative potential determines the oxidative stress and ferroptotic toxicity of airborne particulate matter on pulmonary epithelial cells
by: Bingxue Nie, et al.
Published: (2025-02-01)

Population Distribution of Rats (Rattus argentiventer) and the Damage Intensity on Rice and Other Crops in Pleret, Yogyakarta, Indonesia
by: RR Rukmowati Brotodjojo, et al.
Published: (2023-12-01)

McGregor on damages /
by: Edelman, James
Published: (2021)

McGregor on damages /
by: Edelman, James
Published: (2021)

GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia
by: Lai L, et al.
Published: (2025-02-01)

Quercetin inhibits the biological activity of endometrial cancer by regulating autophagy: A network pharmacology analysis and cellular experimental validation
by: Lingchen Yang, et al.
Published: (2025-02-01)

Effects of prolonged NaHCO3 exposure on the serum immune function, antioxidant capacity, intestinal tight junctions, microbiota, mitochondria, and autophagy in crucian carp (Carassius auratus)
by: Jia Liu, et al.
Published: (2025-01-01)

Chaihu Shugan San and Zuogui Yin synergistically improve premature ovarian failure in a rat model via the PI3K/Akt/mTOR pathway
by: Fei Zhang, et al.
Published: (2025-03-01)

Deferiprone ameliorates cisplatin induced peripheral neurotoxicity via ferritinophagy adjustment
by: Hanan Seddiek, et al.
Published: (2025-02-01)

Application of Nanomaterial-Mediated Ferroptosis Regulation in Kidney Disease
by: Zhu J, et al.
Published: (2025-02-01)

Inducers of Autophagy and Cell Death: Focus on Copper Metabolism
by: Weikang Ling, et al.
Published: (2025-01-01)

Factors influencing incomplete immunization among under five years old children at CHUK hospital, Nyarugenge district, Rwanda
by: Mercy Nwankwo, Chinenye, et al.
Published: (2022)

A new perspective on apoptosis: Its impact on meat and organoleptic quality in different animals
by: Boin Lee, et al.
Published: (2025-01-01)

A Hurricane Preparedness for Citrus Groves
by: Mongi Zekri, et al.
Published: (2017-06-01)

A Hurricane Preparedness for Citrus Groves
by: Mongi Zekri, et al.
Published: (2017-06-01)

PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53
by: Yongli Fan, et al.
Published: (2025-02-01)

Autophagy-lysosome pathway in insulin & glucagon homeostasis
by: Yi Wu, et al.
Published: (2025-02-01)

A ‘torn bag mechanism’ of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)
by: Tamás Visnovitz, et al.
Published: (2025-02-01)