Increase in treatment compliance reveals new options of treatment of gastroesophageal reflux disease
The aim of review. To present update on the causes of insufficient treatment response to proton pump inhibitors (PPI) at gastroesophageal reflux disease (GERD) and to inform on the options of increasing patients’ compliance.Summary. Decline of treatment compliance remains to be one of the principal...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2015-05-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/997 |
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| author | Yu. V. Yevsyutina A. S. Trukhmanov |
| author_facet | Yu. V. Yevsyutina A. S. Trukhmanov |
| author_sort | Yu. V. Yevsyutina |
| collection | DOAJ |
| description | The aim of review. To present update on the causes of insufficient treatment response to proton pump inhibitors (PPI) at gastroesophageal reflux disease (GERD) and to inform on the options of increasing patients’ compliance.Summary. Decline of treatment compliance remains to be one of the principal causes of refractory course of gastroesophageal reflux disease. Existing PPIs have some limitations — necessity of intake strictly before meal and short action period. Dexlansoprazole in double delayed release form allows intake without relation to food intake that allows to increase compliance to treatment.Conclusion. The wide prevalence of GERD dictates necessity of search of new effective agents. Thus one of the principal causes of refractory course of disease is decreased adherence to treatment. Application of new PPI i.e. dexlansoprazole with once per day intake will allow to increase compliance to treatment and to reduce frequency and intensity of symptoms both at erosive esophagitis and non-erosive reflux disease. |
| format | Article |
| id | doaj-art-86257a3e0c0848a69b39be85bb7d4b35 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2015-05-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-86257a3e0c0848a69b39be85bb7d4b352025-02-10T16:14:33ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732015-05-0125249605Increase in treatment compliance reveals new options of treatment of gastroesophageal reflux diseaseYu. V. Yevsyutina0A. S. Trukhmanov1State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university»State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university»The aim of review. To present update on the causes of insufficient treatment response to proton pump inhibitors (PPI) at gastroesophageal reflux disease (GERD) and to inform on the options of increasing patients’ compliance.Summary. Decline of treatment compliance remains to be one of the principal causes of refractory course of gastroesophageal reflux disease. Existing PPIs have some limitations — necessity of intake strictly before meal and short action period. Dexlansoprazole in double delayed release form allows intake without relation to food intake that allows to increase compliance to treatment.Conclusion. The wide prevalence of GERD dictates necessity of search of new effective agents. Thus one of the principal causes of refractory course of disease is decreased adherence to treatment. Application of new PPI i.e. dexlansoprazole with once per day intake will allow to increase compliance to treatment and to reduce frequency and intensity of symptoms both at erosive esophagitis and non-erosive reflux disease.https://www.gastro-j.ru/jour/article/view/997gastroesophageal reflux diseaseproton pump inhibitorsdexlansoprazoletreatment compliance |
| spellingShingle | Yu. V. Yevsyutina A. S. Trukhmanov Increase in treatment compliance reveals new options of treatment of gastroesophageal reflux disease Российский журнал гастроэнтерологии, гепатологии, колопроктологии gastroesophageal reflux disease proton pump inhibitors dexlansoprazole treatment compliance |
| title | Increase in treatment compliance reveals new options of treatment of gastroesophageal reflux disease |
| title_full | Increase in treatment compliance reveals new options of treatment of gastroesophageal reflux disease |
| title_fullStr | Increase in treatment compliance reveals new options of treatment of gastroesophageal reflux disease |
| title_full_unstemmed | Increase in treatment compliance reveals new options of treatment of gastroesophageal reflux disease |
| title_short | Increase in treatment compliance reveals new options of treatment of gastroesophageal reflux disease |
| title_sort | increase in treatment compliance reveals new options of treatment of gastroesophageal reflux disease |
| topic | gastroesophageal reflux disease proton pump inhibitors dexlansoprazole treatment compliance |
| url | https://www.gastro-j.ru/jour/article/view/997 |
| work_keys_str_mv | AT yuvyevsyutina increaseintreatmentcompliancerevealsnewoptionsoftreatmentofgastroesophagealrefluxdisease AT astrukhmanov increaseintreatmentcompliancerevealsnewoptionsoftreatmentofgastroesophagealrefluxdisease |