Spectrum of endoscopic gastric subepithelial lesions encountered on EUS-FNA: A single center experience
Background and Objectives: Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is a minimally invasive and reliable non-surgical technique for the diagnosis of gastrointestinal lesions. The present study aimed to evaluate the spectrum of lesions encountered in the gastric subepithelium on...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-04-01
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| Series: | Indian Journal of Pathology and Microbiology |
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| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_636_22 |
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| author | Poojan Agarwal Pooja Bakshi Kusum Verma Vikas Singla Anil Arora |
| author_facet | Poojan Agarwal Pooja Bakshi Kusum Verma Vikas Singla Anil Arora |
| author_sort | Poojan Agarwal |
| collection | DOAJ |
| description | Background and Objectives:
Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is a minimally invasive and reliable non-surgical technique for the diagnosis of gastrointestinal lesions. The present study aimed to evaluate the spectrum of lesions encountered in the gastric subepithelium on EUS-FNA at a tertiary care center.
Materials and Methods:
Archival data of all patients undergoing EUS-FNA for gastric submucosal lesions over a period of 5 years was retrieved. Patient demographics, clinical presentation, and EUS findings were recorded along with the FNA results.
Results:
A total of 78 EUS-FNA samples were analyzed. Material was adequate in 62 cases (79.48%) and inadequate in 16 cases (12.82%) patients due to scant cellularity. Of the adequate samples, 34 (43.5%) were reported as neoplastic while 20 (25.64%) were non-neoplastic, and 8 (10.25%) were reported as suspicious of a neoplasm. In the neoplastic category, the predominant diagnosis was of spindle cell neoplasm comprising gastrointestinal stromal tumor (13), benign neural tumor (03), leiomyoma (02), and spindle cell tumors (03). The latter could not be categorized further due to a lack of IHC material. The next common diagnosis was adenocarcinoma (06) followed by neuroendocrine tumor (02) and poorly differentiated carcinoma (01). The non-neoplastic lesions included non-specific pathology (15), inflammatory lesions (08), and one case each of tuberculosis, pancreatic rest, and Brunner gland hamartoma. Cell blocks for ancillary testing were available in 54 cases (65.23%) and follow-up was available in 42 cases (53.84%).
Conclusion:
EUS-FNA is a good modality for the diagnosis of gastric submucosal lesions with a high diagnostic yield. |
| format | Article |
| id | doaj-art-886295ad7a0e4f4b9a0df250bf51d936 |
| institution | Kabale University |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-886295ad7a0e4f4b9a0df250bf51d9362025-02-07T13:58:15ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-04-0167237437810.4103/ijpm.ijpm_636_22Spectrum of endoscopic gastric subepithelial lesions encountered on EUS-FNA: A single center experiencePoojan AgarwalPooja BakshiKusum VermaVikas SinglaAnil AroraBackground and Objectives: Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is a minimally invasive and reliable non-surgical technique for the diagnosis of gastrointestinal lesions. The present study aimed to evaluate the spectrum of lesions encountered in the gastric subepithelium on EUS-FNA at a tertiary care center. Materials and Methods: Archival data of all patients undergoing EUS-FNA for gastric submucosal lesions over a period of 5 years was retrieved. Patient demographics, clinical presentation, and EUS findings were recorded along with the FNA results. Results: A total of 78 EUS-FNA samples were analyzed. Material was adequate in 62 cases (79.48%) and inadequate in 16 cases (12.82%) patients due to scant cellularity. Of the adequate samples, 34 (43.5%) were reported as neoplastic while 20 (25.64%) were non-neoplastic, and 8 (10.25%) were reported as suspicious of a neoplasm. In the neoplastic category, the predominant diagnosis was of spindle cell neoplasm comprising gastrointestinal stromal tumor (13), benign neural tumor (03), leiomyoma (02), and spindle cell tumors (03). The latter could not be categorized further due to a lack of IHC material. The next common diagnosis was adenocarcinoma (06) followed by neuroendocrine tumor (02) and poorly differentiated carcinoma (01). The non-neoplastic lesions included non-specific pathology (15), inflammatory lesions (08), and one case each of tuberculosis, pancreatic rest, and Brunner gland hamartoma. Cell blocks for ancillary testing were available in 54 cases (65.23%) and follow-up was available in 42 cases (53.84%). Conclusion: EUS-FNA is a good modality for the diagnosis of gastric submucosal lesions with a high diagnostic yield.https://journals.lww.com/10.4103/ijpm.ijpm_636_22brunner gland hamartomaeus-fnagastric submucosagist |
| spellingShingle | Poojan Agarwal Pooja Bakshi Kusum Verma Vikas Singla Anil Arora Spectrum of endoscopic gastric subepithelial lesions encountered on EUS-FNA: A single center experience Indian Journal of Pathology and Microbiology brunner gland hamartoma eus-fna gastric submucosa gist |
| title | Spectrum of endoscopic gastric subepithelial lesions encountered on EUS-FNA: A single center experience |
| title_full | Spectrum of endoscopic gastric subepithelial lesions encountered on EUS-FNA: A single center experience |
| title_fullStr | Spectrum of endoscopic gastric subepithelial lesions encountered on EUS-FNA: A single center experience |
| title_full_unstemmed | Spectrum of endoscopic gastric subepithelial lesions encountered on EUS-FNA: A single center experience |
| title_short | Spectrum of endoscopic gastric subepithelial lesions encountered on EUS-FNA: A single center experience |
| title_sort | spectrum of endoscopic gastric subepithelial lesions encountered on eus fna a single center experience |
| topic | brunner gland hamartoma eus-fna gastric submucosa gist |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_636_22 |
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