Nanocellulose Targets Regenerative Medicine
The term “nanocellulose” encompasses a wide range of cellulose-derived nanomaterials, which are characterized by their diverse morphologies and chemical structures at the nanometer scale. In recent years, there has been a remarkable increase in the use of nanocellulose in regenerative medicine. Of p...
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North Carolina State University
2025-02-01
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| Series: | BioResources |
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| Online Access: | https://ojs.bioresources.com/index.php/BRJ/article/view/24372 |
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| _version_ | 1823859622625148928 |
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| author | Takuya Kitaoka |
| author_facet | Takuya Kitaoka |
| author_sort | Takuya Kitaoka |
| collection | DOAJ |
| description | The term “nanocellulose” encompasses a wide range of cellulose-derived nanomaterials, which are characterized by their diverse morphologies and chemical structures at the nanometer scale. In recent years, there has been a remarkable increase in the use of nanocellulose in regenerative medicine. Of particular interest is the in vitro culture of pluripotent stem cells, which has led to a growing demand for animal-free media and scaffolds in stem cell culture. Extracellular matrix (ECM) plays a pivotal role in regulating the proliferation and differentiation of stem cells, with fibrous collagen and glycosaminoglycans serving as structural and functional supports. In this context, nanocellulose has garnered significant interest as potential ECM mimetics, due to its rigid fiber form and its regular interfacial structures. The use of natural polysaccharide nanofibers would represent a promising avenue for the functional design of animal-free cell culture scaffolds, with the potential to significantly advance the regulation of stem cell culture in regenerative medicine. |
| format | Article |
| id | doaj-art-899c35b61b3f489582445d4e196b3739 |
| institution | Kabale University |
| issn | 1930-2126 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | North Carolina State University |
| record_format | Article |
| series | BioResources |
| spelling | doaj-art-899c35b61b3f489582445d4e196b37392025-02-11T00:00:29ZengNorth Carolina State UniversityBioResources1930-21262025-02-01202246424672649Nanocellulose Targets Regenerative MedicineTakuya Kitaoka0https://orcid.org/0000-0003-1691-9946Department of Agro-Environmental Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, JapanThe term “nanocellulose” encompasses a wide range of cellulose-derived nanomaterials, which are characterized by their diverse morphologies and chemical structures at the nanometer scale. In recent years, there has been a remarkable increase in the use of nanocellulose in regenerative medicine. Of particular interest is the in vitro culture of pluripotent stem cells, which has led to a growing demand for animal-free media and scaffolds in stem cell culture. Extracellular matrix (ECM) plays a pivotal role in regulating the proliferation and differentiation of stem cells, with fibrous collagen and glycosaminoglycans serving as structural and functional supports. In this context, nanocellulose has garnered significant interest as potential ECM mimetics, due to its rigid fiber form and its regular interfacial structures. The use of natural polysaccharide nanofibers would represent a promising avenue for the functional design of animal-free cell culture scaffolds, with the potential to significantly advance the regulation of stem cell culture in regenerative medicine.https://ojs.bioresources.com/index.php/BRJ/article/view/24372cellulose nanofibersurface modificationextracellular matrix mimeticsxeno-freestem cell |
| spellingShingle | Takuya Kitaoka Nanocellulose Targets Regenerative Medicine BioResources cellulose nanofiber surface modification extracellular matrix mimetics xeno-free stem cell |
| title | Nanocellulose Targets Regenerative Medicine |
| title_full | Nanocellulose Targets Regenerative Medicine |
| title_fullStr | Nanocellulose Targets Regenerative Medicine |
| title_full_unstemmed | Nanocellulose Targets Regenerative Medicine |
| title_short | Nanocellulose Targets Regenerative Medicine |
| title_sort | nanocellulose targets regenerative medicine |
| topic | cellulose nanofiber surface modification extracellular matrix mimetics xeno-free stem cell |
| url | https://ojs.bioresources.com/index.php/BRJ/article/view/24372 |
| work_keys_str_mv | AT takuyakitaoka nanocellulosetargetsregenerativemedicine |