Probiotics in the Modern World

Aim of review. The review highlights modern concepts of the role of microbiome in sustaining the human body, the place of probiotics in treatment and prevention of pathologies related to disorders in healthy microbiota.Key points. Microbiome is a unique panorganismal system normally maintaining self...

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Main Authors: Y. P. Uspenskiy, Y. A. Fominykh, K. N. Nadzhafova, S. V. Polyushkin
Format: Article
Language:Russian
Published: Gastro LLC 2020-07-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Subjects:
Online Access:https://www.gastro-j.ru/jour/article/view/470
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author Y. P. Uspenskiy
Y. A. Fominykh
K. N. Nadzhafova
S. V. Polyushkin
author_facet Y. P. Uspenskiy
Y. A. Fominykh
K. N. Nadzhafova
S. V. Polyushkin
author_sort Y. P. Uspenskiy
collection DOAJ
description Aim of review. The review highlights modern concepts of the role of microbiome in sustaining the human body, the place of probiotics in treatment and prevention of pathologies related to disorders in healthy microbiota.Key points. Microbiome is a unique panorganismal system normally maintaining self-equilibrium and possessing a vast and diverse functionality. Imbalance in normal microbiota can be assisted by probiotics, i.e. living microorganisms that sustain health of the host when being supplied in adequate amounts. Alike normal microflora, probiotic strains incorporate into general metabolism by mediating a spectrum of functions, e.g. maintaining colonisation resistance, nutrient metabolism, supplying the host with vital metabolites, regulation of local and adaptive immune responses, enhancing the intestinal barrier. Probiotics are applied in various diseases associated with general imbalances of the organism. Modern probiotic preparations are characterised by acid- and antibiotic-resistivity and safety, thus being suitable for treating gut microbiome-associated disorders in various age groups.Conclusion. Probiotic strains, as well as medications designed on their basis, are widely applied and show good promise. Further research into their properties will advance the prospects of probiotic treatment.
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institution Kabale University
issn 1382-4376
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language Russian
publishDate 2020-07-01
publisher Gastro LLC
record_format Article
series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-8b11d2bc3f59470aa403a3b74cf8c8652025-02-10T16:14:36ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732020-07-01303243510.22416/1382-4376-2020-30-3-24-35363Probiotics in the Modern WorldY. P. Uspenskiy0Y. A. Fominykh1K. N. Nadzhafova2S. V. Polyushkin3St. Petersburg State Pediatric Medical University; Pavlov First St. Petersburg State Medical UniversityPavlov First St. Petersburg State Medical UniversitySt. Petersburg State Pediatric Medical UniversityRehabilitation CenterAim of review. The review highlights modern concepts of the role of microbiome in sustaining the human body, the place of probiotics in treatment and prevention of pathologies related to disorders in healthy microbiota.Key points. Microbiome is a unique panorganismal system normally maintaining self-equilibrium and possessing a vast and diverse functionality. Imbalance in normal microbiota can be assisted by probiotics, i.e. living microorganisms that sustain health of the host when being supplied in adequate amounts. Alike normal microflora, probiotic strains incorporate into general metabolism by mediating a spectrum of functions, e.g. maintaining colonisation resistance, nutrient metabolism, supplying the host with vital metabolites, regulation of local and adaptive immune responses, enhancing the intestinal barrier. Probiotics are applied in various diseases associated with general imbalances of the organism. Modern probiotic preparations are characterised by acid- and antibiotic-resistivity and safety, thus being suitable for treating gut microbiome-associated disorders in various age groups.Conclusion. Probiotic strains, as well as medications designed on their basis, are widely applied and show good promise. Further research into their properties will advance the prospects of probiotic treatment.https://www.gastro-j.ru/jour/article/view/470microbiotaprobiotics<i>lactobacillus acidophilus</i><i>bifidobacterium lactis</i>
spellingShingle Y. P. Uspenskiy
Y. A. Fominykh
K. N. Nadzhafova
S. V. Polyushkin
Probiotics in the Modern World
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
microbiota
probiotics
<i>lactobacillus acidophilus</i>
<i>bifidobacterium lactis</i>
title Probiotics in the Modern World
title_full Probiotics in the Modern World
title_fullStr Probiotics in the Modern World
title_full_unstemmed Probiotics in the Modern World
title_short Probiotics in the Modern World
title_sort probiotics in the modern world
topic microbiota
probiotics
<i>lactobacillus acidophilus</i>
<i>bifidobacterium lactis</i>
url https://www.gastro-j.ru/jour/article/view/470
work_keys_str_mv AT ypuspenskiy probioticsinthemodernworld
AT yafominykh probioticsinthemodernworld
AT knnadzhafova probioticsinthemodernworld
AT svpolyushkin probioticsinthemodernworld