ZBiotics ameliorates T2DM-induced histopathological damage in liver, kidney and adipose tissues by modulating the NOD-like receptor signaling in Wistar rats

ZBiotics ameliorates T2DM-induced histopathological damage in liver, kidney and adipose tissues by modulating the NOD-like receptor signaling in Wistar rats

Abstract Probiotics serve as promising candidates in type 2 diabetes mellitus (T2DM) therapy. Not only they presumably reduce the T2DM prevalence, but also keep down its complications. In the present study, we explored the beneficial impact of ZBiotics, an engineered probiotic, on T2DM Wistar rats....

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Bibliographic Details
Main Authors: Mohammed Esawie, Marwa Matboli, Mariam Sameh Bushra, Amany H. Hasanin, Eman Kamal Habib, Reham Hussein Mohamed, Hebatalla Said Ali
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Type 2 diabetes mellitus
ZBiotics
TNF-alpha
LC3B
STING-NOD
Online Access:https://doi.org/10.1186/s13098-025-01600-3
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