Repetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgia
Abstract Background Fibromyalgia is characterized by widespread musculoskeletal pain and tenderness. It is also frequently associated with mood disorders, tiredness, sleep disturbances, and cognitive dysfunction. Repetitive transcranial magnetic stimulation (rTMS) is an emerging nonpharmacological t...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2025-02-01
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| Series: | Egyptian Rheumatology and Rehabilitation |
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| Online Access: | https://doi.org/10.1186/s43166-025-00302-y |
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| author | Rawan M. El Shahat Mona A. El Sebaie Sahar F. Ahmed Shereen I. Fawaz Marwa A. Kamel Marwa A. Nassef |
| author_facet | Rawan M. El Shahat Mona A. El Sebaie Sahar F. Ahmed Shereen I. Fawaz Marwa A. Kamel Marwa A. Nassef |
| author_sort | Rawan M. El Shahat |
| collection | DOAJ |
| description | Abstract Background Fibromyalgia is characterized by widespread musculoskeletal pain and tenderness. It is also frequently associated with mood disorders, tiredness, sleep disturbances, and cognitive dysfunction. Repetitive transcranial magnetic stimulation (rTMS) is an emerging nonpharmacological therapeutic option for fibromyalgia. rTMS involves an electromagnetic coil placed on the scalp that is rapidly turned on and off to generate short magnetic pulses to the brain (2). rTMS can reduce chronic pain by triggering inhibitory neural pathways at the level of the dorsal horn of the spinal cord. It can improve motor function and alleviate psychiatric symptoms, including depression and anxiety, in many diseases (7). Aim of the work The study aimed to evaluate the role of repetitive transcranial magnetic stimulation (rTMS) in treating fibromyalgia. Results Highly significant improvement in feel-good and work-missed scores by FIQ being lower in the case group compared to the control group (p-values 0.008 and 0.003 respectively). On comparing the control and case groups regarding anxiety and depression using the HADS questionnaire and fatigue assessment using the SF36 questionnaire after rTMS sessions, there was a statistically significant lower depression score in the case group compared to the control group (p-value of 0.024), and statistically significant higher energy/fatigue scores in the case group compared to the control group with (p-value = 0.004). Conclusion This study demonstrated that rTMS relieved pain, reduced anxiety, depression, and fatigue and enhanced quality of life in patients with fibromyalgia. |
| format | Article |
| id | doaj-art-8f1c2d1ed506403194bc879c571e288e |
| institution | Kabale University |
| issn | 2090-3235 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Egyptian Rheumatology and Rehabilitation |
| spelling | doaj-art-8f1c2d1ed506403194bc879c571e288e2025-02-09T12:40:44ZengSpringerOpenEgyptian Rheumatology and Rehabilitation2090-32352025-02-0152111310.1186/s43166-025-00302-yRepetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgiaRawan M. El Shahat0Mona A. El Sebaie1Sahar F. Ahmed2Shereen I. Fawaz3Marwa A. Kamel4Marwa A. Nassef5Rheumatology, Rehabilitation and Physical Medicine. Faculty of Medicine, Ain Shams UniversityRheumatology, Rehabilitation and Physical Medicine. Faculty of Medicine, Ain Shams UniversityRheumatology, Rehabilitation and Physical Medicine. Faculty of Medicine, Ain Shams UniversityRheumatology, Rehabilitation and Physical Medicine. Faculty of Medicine, Ain Shams UniversityRheumatology, Rehabilitation and Physical Medicine. Faculty of Medicine, Ain Shams UniversityRheumatology, Rehabilitation and Physical Medicine. Faculty of Medicine, Ain Shams UniversityAbstract Background Fibromyalgia is characterized by widespread musculoskeletal pain and tenderness. It is also frequently associated with mood disorders, tiredness, sleep disturbances, and cognitive dysfunction. Repetitive transcranial magnetic stimulation (rTMS) is an emerging nonpharmacological therapeutic option for fibromyalgia. rTMS involves an electromagnetic coil placed on the scalp that is rapidly turned on and off to generate short magnetic pulses to the brain (2). rTMS can reduce chronic pain by triggering inhibitory neural pathways at the level of the dorsal horn of the spinal cord. It can improve motor function and alleviate psychiatric symptoms, including depression and anxiety, in many diseases (7). Aim of the work The study aimed to evaluate the role of repetitive transcranial magnetic stimulation (rTMS) in treating fibromyalgia. Results Highly significant improvement in feel-good and work-missed scores by FIQ being lower in the case group compared to the control group (p-values 0.008 and 0.003 respectively). On comparing the control and case groups regarding anxiety and depression using the HADS questionnaire and fatigue assessment using the SF36 questionnaire after rTMS sessions, there was a statistically significant lower depression score in the case group compared to the control group (p-value of 0.024), and statistically significant higher energy/fatigue scores in the case group compared to the control group with (p-value = 0.004). Conclusion This study demonstrated that rTMS relieved pain, reduced anxiety, depression, and fatigue and enhanced quality of life in patients with fibromyalgia.https://doi.org/10.1186/s43166-025-00302-yRepetitive transcranial magnetic stimulationFibromyalgia |
| spellingShingle | Rawan M. El Shahat Mona A. El Sebaie Sahar F. Ahmed Shereen I. Fawaz Marwa A. Kamel Marwa A. Nassef Repetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgia Egyptian Rheumatology and Rehabilitation Repetitive transcranial magnetic stimulation Fibromyalgia |
| title | Repetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgia |
| title_full | Repetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgia |
| title_fullStr | Repetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgia |
| title_full_unstemmed | Repetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgia |
| title_short | Repetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgia |
| title_sort | repetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgia |
| topic | Repetitive transcranial magnetic stimulation Fibromyalgia |
| url | https://doi.org/10.1186/s43166-025-00302-y |
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