Automated quantification of axonal and myelin changes in contusion, dislocation, and distraction spinal cord injuries: Insights into targeted remyelination and axonal regeneration

Automated quantification of axonal and myelin changes in contusion, dislocation, and distraction spinal cord injuries: Insights into targeted remyelination and axonal regeneration

Quantifying axons and myelin is essential for understanding spinal cord injury (SCI) mechanisms and developing targeted therapies. This study proposes and validates an automated method to measure axons and myelin, applied to compare contusion, dislocation, and distraction SCIs in a rat model. Spinal...

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Bibliographic Details
Main Authors: Xuan Li, Yuan He, Fangyao Chen, Xin Tong, Yunlong Fan, Yuzhe Langzhou, Jie Liu, Kinon Chen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Brain Research Bulletin
Subjects:
Spinal cord injury
Axons
Myelin
Neurodegeneration
Remyelination
Quantification
Online Access:http://www.sciencedirect.com/science/article/pii/S036192302500005X
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