Exosomes and their distinct integrins transfer the characteristics of oxaliplatin- and 5-FU-resistant behaviors in colorectal cancer cells

Exosomes and their distinct integrins transfer the characteristics of oxaliplatin- and 5-FU-resistant behaviors in colorectal cancer cells

Abstract Background Exosomes are communication carriers and suitable biomarker candidates due to their cargoes with specific dynamic profiles. Integrins, as valuable prognostic markers in cancer, have importance in exosome-cell interaction. However, the role of exosome integrins in chemoresistant co...

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Bibliographic Details
Main Authors: Zeynab Vakili-Ghartavol, Hoda Deli, Amir Shadboorestan, Roxana Sahebnasagh, Elahe Motevaseli, Mohammad Hossein Ghahremani
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Molecular Medicine
Subjects:
ITG
Exosome
Drug resistance
5-FU
Oxaliplatin
Colorectal cancer
Online Access:https://doi.org/10.1186/s10020-025-01110-y
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