Modern Possibilities of Using Lactulose in Clinical Practice

Aim of  the publication. To present an overview  of current literature data on the possibilities of application  of lactulose in clinical practice.Key findings. Lactulose is a synthetic disaccharide belonging to the class of osmotic laxatives. Officially  permitted indications for its appointment in...

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Main Author: A. A. Sheptulin
Format: Article
Language:Russian
Published: Gastro LLC 2023-11-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/901
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author A. A. Sheptulin
author_facet A. A. Sheptulin
author_sort A. A. Sheptulin
collection DOAJ
description Aim of  the publication. To present an overview  of current literature data on the possibilities of application  of lactulose in clinical practice.Key findings. Lactulose is a synthetic disaccharide belonging to the class of osmotic laxatives. Officially  permitted indications for its appointment in Russian Federation are functional constipation (including in children, the elderly and senile, pregnant women and women in postpartum period), an obstipation type of irritable bowel syndrome, the need to soften the consistency of feces in hemorrhoids and anal fissures, after operations on the colon and anorectal area,   as well as hepatic encephalopathy.  Other  indications include preparation for colonoscopy, treatment and prevention of disorders of the intestinal microbiota, prevention  of constipation in oncological  patients receiving narcotic analgesics, as well as patients on artificial lung ventilation.Conclusion. Lactulose is a highly effective  and safe drug, which combines osmotic laxative effect with expressed prebiotic action and is used in a wide clinical practice.
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series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-94d14c49baad49fab9bd34514c55a9f92025-02-10T16:14:38ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732023-11-01334707510.22416/1382-4376-2023-33-4-70-75564Modern Possibilities of Using Lactulose in Clinical PracticeA. A. Sheptulin0I.M. Sechenov First Moscow State Medical University (Sechenov University)Aim of  the publication. To present an overview  of current literature data on the possibilities of application  of lactulose in clinical practice.Key findings. Lactulose is a synthetic disaccharide belonging to the class of osmotic laxatives. Officially  permitted indications for its appointment in Russian Federation are functional constipation (including in children, the elderly and senile, pregnant women and women in postpartum period), an obstipation type of irritable bowel syndrome, the need to soften the consistency of feces in hemorrhoids and anal fissures, after operations on the colon and anorectal area,   as well as hepatic encephalopathy.  Other  indications include preparation for colonoscopy, treatment and prevention of disorders of the intestinal microbiota, prevention  of constipation in oncological  patients receiving narcotic analgesics, as well as patients on artificial lung ventilation.Conclusion. Lactulose is a highly effective  and safe drug, which combines osmotic laxative effect with expressed prebiotic action and is used in a wide clinical practice.https://www.gastro-j.ru/jour/article/view/901lactulosefunctional constipationobstipation type of irritable bowel syndromehepatic encephalopathy
spellingShingle A. A. Sheptulin
Modern Possibilities of Using Lactulose in Clinical Practice
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
lactulose
functional constipation
obstipation type of irritable bowel syndrome
hepatic encephalopathy
title Modern Possibilities of Using Lactulose in Clinical Practice
title_full Modern Possibilities of Using Lactulose in Clinical Practice
title_fullStr Modern Possibilities of Using Lactulose in Clinical Practice
title_full_unstemmed Modern Possibilities of Using Lactulose in Clinical Practice
title_short Modern Possibilities of Using Lactulose in Clinical Practice
title_sort modern possibilities of using lactulose in clinical practice
topic lactulose
functional constipation
obstipation type of irritable bowel syndrome
hepatic encephalopathy
url https://www.gastro-j.ru/jour/article/view/901
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