Biochemical Markers as Predictor of Preterm Labor - and Their Clinical Relevance - the Current Status
Preterm birth is associated with significant perinatal morbidity and mortality. Spontaneous preterm birth accounts for upto 75% of all preterm births. A number of maternal and fetal characteristics have been associated with preterm birth. With better understanding of the pathophysiology of preterm...
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| Format: | Article |
| Language: | English |
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Medical Network
2022-12-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
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| Online Access: | https://gorm.com.tr/index.php/GORM/article/view/1108 |
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| author | Suneeta Singh Madhusudhan Dey Sanjay Singh Shibu Sasidharan |
| author_facet | Suneeta Singh Madhusudhan Dey Sanjay Singh Shibu Sasidharan |
| author_sort | Suneeta Singh |
| collection | DOAJ |
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Preterm birth is associated with significant perinatal morbidity and mortality. Spontaneous preterm birth accounts for upto 75% of all preterm births. A number of maternal and fetal characteristics have been associated with preterm birth. With better understanding of the pathophysiology of preterm birth, various biochemical markers have been studied extensively to predict the preterm birth efficiently so as to intervene appropriately and timely in the cases that would benefit from treatment. This paper provides a summary of the current literature on the use of biochemical markers in predicting spontaneous preterm birth in symptomatic and high risk-asymptomatic women. Evidence from the literature suggests cervico vaginal fetal fibronectin,interleukin-6, phosphorylated Insulin-like growth factor binding protein-1(phIGFBP1), placental alpha macroglobulin-1 (PAMG-1) and serum
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| format | Article |
| id | doaj-art-9533f3b7ad8643e4846fc91df9b0f0ac |
| institution | Kabale University |
| issn | 1300-4751 2602-4918 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj-art-9533f3b7ad8643e4846fc91df9b0f0ac2025-02-11T21:16:19ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182022-12-0128310.21613/GORM.2020.1108Biochemical Markers as Predictor of Preterm Labor - and Their Clinical Relevance - the Current StatusSuneeta Singh0Madhusudhan Dey1Sanjay Singh2Shibu Sasidharan3Lt Col Suneeta Singh Asst Professor, Department of Obstetrics and Gynaecology Base Hospital, Delhi Cantt New Delhi IndiaColonel Madhusudan Dey Associate Professor Department of Obstetrics and Gynaecology Base Hospital Delhi Cantt New DelhiColonel Sanjay Singh Professor Department of Obstetrics and Gynaecology Base Hospital Delhi Cantt New DelhiLt Col Shibu Sasidharan Associate Professor Department of Anaesthesia and Critical Care Level III UN hospital Preterm birth is associated with significant perinatal morbidity and mortality. Spontaneous preterm birth accounts for upto 75% of all preterm births. A number of maternal and fetal characteristics have been associated with preterm birth. With better understanding of the pathophysiology of preterm birth, various biochemical markers have been studied extensively to predict the preterm birth efficiently so as to intervene appropriately and timely in the cases that would benefit from treatment. This paper provides a summary of the current literature on the use of biochemical markers in predicting spontaneous preterm birth in symptomatic and high risk-asymptomatic women. Evidence from the literature suggests cervico vaginal fetal fibronectin,interleukin-6, phosphorylated Insulin-like growth factor binding protein-1(phIGFBP1), placental alpha macroglobulin-1 (PAMG-1) and serum https://gorm.com.tr/index.php/GORM/article/view/1108preterm birth (PTB)preterm delivery (PTD)phosphorylated Insulin-like growth factor binding protein-1(phIGFBP1)placental alpha macroglobulin-1 (PAMG-1) |
| spellingShingle | Suneeta Singh Madhusudhan Dey Sanjay Singh Shibu Sasidharan Biochemical Markers as Predictor of Preterm Labor - and Their Clinical Relevance - the Current Status Gynecology Obstetrics & Reproductive Medicine preterm birth (PTB) preterm delivery (PTD) phosphorylated Insulin-like growth factor binding protein-1(phIGFBP1) placental alpha macroglobulin-1 (PAMG-1) |
| title | Biochemical Markers as Predictor of Preterm Labor - and Their Clinical Relevance - the Current Status |
| title_full | Biochemical Markers as Predictor of Preterm Labor - and Their Clinical Relevance - the Current Status |
| title_fullStr | Biochemical Markers as Predictor of Preterm Labor - and Their Clinical Relevance - the Current Status |
| title_full_unstemmed | Biochemical Markers as Predictor of Preterm Labor - and Their Clinical Relevance - the Current Status |
| title_short | Biochemical Markers as Predictor of Preterm Labor - and Their Clinical Relevance - the Current Status |
| title_sort | biochemical markers as predictor of preterm labor and their clinical relevance the current status |
| topic | preterm birth (PTB) preterm delivery (PTD) phosphorylated Insulin-like growth factor binding protein-1(phIGFBP1) placental alpha macroglobulin-1 (PAMG-1) |
| url | https://gorm.com.tr/index.php/GORM/article/view/1108 |
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