The dangerous biology of pathogenic germs

The convergence of biotechnologies with other disciplines, including computer science and Artificial Intelligence (AI), may make it possible to carry out dangerous genetic manipulations on pathogenic germs, as the gain-of-function experiments exacerbating virulence, as those carried out on myxovirus...

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Main Author: Berche, Patrick
Format: Article
Language:English
Published: Académie des sciences 2024-09-01
Series:Comptes Rendus Biologies
Subjects:
Online Access:https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.157/
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author Berche, Patrick
author_facet Berche, Patrick
author_sort Berche, Patrick
collection DOAJ
description The convergence of biotechnologies with other disciplines, including computer science and Artificial Intelligence (AI), may make it possible to carry out dangerous genetic manipulations on pathogenic germs, as the gain-of-function experiments exacerbating virulence, as those carried out on myxoviruses and coronaviruses. Moreover, it is now possible to chemically synthesise any microorganism from in silico sequences, including the most dangerous viruses (poxviruses, Ebola, etc.), whose sequences are accessible. It might even be possible to use AI to design new germs that could be used as biological weapons.
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spelling doaj-art-955667e817b742ef968834b8e9f45ecb2025-02-07T10:37:47ZengAcadémie des sciencesComptes Rendus Biologies1768-32382024-09-01347G1778610.5802/crbiol.15710.5802/crbiol.157The dangerous biology of pathogenic germsBerche, Patrick0https://orcid.org/0000-0002-8941-1564Emeritus Professor at the Université Paris Cité, Member of the Académie Nationale de Médecine, FranceThe convergence of biotechnologies with other disciplines, including computer science and Artificial Intelligence (AI), may make it possible to carry out dangerous genetic manipulations on pathogenic germs, as the gain-of-function experiments exacerbating virulence, as those carried out on myxoviruses and coronaviruses. Moreover, it is now possible to chemically synthesise any microorganism from in silico sequences, including the most dangerous viruses (poxviruses, Ebola, etc.), whose sequences are accessible. It might even be possible to use AI to design new germs that could be used as biological weapons.https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.157/Gain-of-functionSynthetic biologyBiological weaponsBiosecurity
spellingShingle Berche, Patrick
The dangerous biology of pathogenic germs
Comptes Rendus Biologies
Gain-of-function
Synthetic biology
Biological weapons
Biosecurity
title The dangerous biology of pathogenic germs
title_full The dangerous biology of pathogenic germs
title_fullStr The dangerous biology of pathogenic germs
title_full_unstemmed The dangerous biology of pathogenic germs
title_short The dangerous biology of pathogenic germs
title_sort dangerous biology of pathogenic germs
topic Gain-of-function
Synthetic biology
Biological weapons
Biosecurity
url https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.157/
work_keys_str_mv AT berchepatrick thedangerousbiologyofpathogenicgerms
AT berchepatrick dangerousbiologyofpathogenicgerms