Triplet Pregnancy with Partial Hydatidiform Mole Coexisting with Two Fetuses after Ovulation Induction and Intrauterine Insemination

Partial hydatidiform mole with dichorionic twin fetuses is extremely rare condition, and only three cases have been reported before. Twenty- five years old primigravida having a trizygotic triplet pregnancy that has been conceived by ovulation induction and intrauterine insemination was referred to...

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Main Authors: Mehmet Serdar Kütük, Mehmet Dolanbay, Hilal Akalın, Mahmut Tuncay Özgün, Turhan Öktem, Munis Dündar, Ercan Aygen
Format: Article
Language:English
Published: Medical Network 2015-12-01
Series:Gynecology Obstetrics & Reproductive Medicine
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Online Access:https://gorm.com.tr/index.php/GORM/article/view/13
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author Mehmet Serdar Kütük
Mehmet Dolanbay
Hilal Akalın
Mahmut Tuncay Özgün
Turhan Öktem
Munis Dündar
Ercan Aygen
author_facet Mehmet Serdar Kütük
Mehmet Dolanbay
Hilal Akalın
Mahmut Tuncay Özgün
Turhan Öktem
Munis Dündar
Ercan Aygen
author_sort Mehmet Serdar Kütük
collection DOAJ
description Partial hydatidiform mole with dichorionic twin fetuses is extremely rare condition, and only three cases have been reported before. Twenty- five years old primigravida having a trizygotic triplet pregnancy that has been conceived by ovulation induction and intrauterine insemination was referred to our department for threatened abortion. The fetus B with molar placenta has been selectively terminated at 11th weeks and the pregnancy was complicated with preeclampsia, hyperthyroidism, and culminated in spontaneous abortion at 20th weeks. After the abortion, the pathologic evaluation suggested partial mole, and genetic evaluation confirmed the diagnosis. The postpartum course complicated with persistent trophoblastic disease that well responded to four course of methotrexate therapy. The optimal management of partial hydatidiform mole coexistent with two fetuses is currently uncertain. The choice of continuing the pregnancy must be individualized, depending on the patient condition. These patients should be carefully followed after the pregnancy for persistent trophoblastic disease.
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institution Kabale University
issn 1300-4751
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publishDate 2015-12-01
publisher Medical Network
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series Gynecology Obstetrics & Reproductive Medicine
spelling doaj-art-958bf9cef697466ca1f5ee2183278c8e2025-02-11T21:26:17ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182015-12-0121313Triplet Pregnancy with Partial Hydatidiform Mole Coexisting with Two Fetuses after Ovulation Induction and Intrauterine InseminationMehmet Serdar Kütük0Mehmet Dolanbay1Hilal Akalın2Mahmut Tuncay Özgün3Turhan Öktem4Munis Dündar5Ercan Aygen6Erciyes University Faculty of Medicine Department of Obstetrics and Gynaecology, KayseriErciyes University Faculty of Medicine Department of Obstetrics and Gynaecology, KayseriErciyes University Faculty of Medicine Department of Genetics, KayseriErciyes University Faculty of Medicine Department of Obstetrics and Gynaecology, KayseriErciyes University Faculty of Medicine Department of Pathology, KayseriErciyes University Faculty of Medicine Department of Genetics, KayseriErciyes University Faculty of Medicine Department of Obstetrics and Gynaecology, KayseriPartial hydatidiform mole with dichorionic twin fetuses is extremely rare condition, and only three cases have been reported before. Twenty- five years old primigravida having a trizygotic triplet pregnancy that has been conceived by ovulation induction and intrauterine insemination was referred to our department for threatened abortion. The fetus B with molar placenta has been selectively terminated at 11th weeks and the pregnancy was complicated with preeclampsia, hyperthyroidism, and culminated in spontaneous abortion at 20th weeks. After the abortion, the pathologic evaluation suggested partial mole, and genetic evaluation confirmed the diagnosis. The postpartum course complicated with persistent trophoblastic disease that well responded to four course of methotrexate therapy. The optimal management of partial hydatidiform mole coexistent with two fetuses is currently uncertain. The choice of continuing the pregnancy must be individualized, depending on the patient condition. These patients should be carefully followed after the pregnancy for persistent trophoblastic disease.https://gorm.com.tr/index.php/GORM/article/view/13Triplet pregnancyPartial hydatidiform moleOvulation inductionIntrauterine insemination
spellingShingle Mehmet Serdar Kütük
Mehmet Dolanbay
Hilal Akalın
Mahmut Tuncay Özgün
Turhan Öktem
Munis Dündar
Ercan Aygen
Triplet Pregnancy with Partial Hydatidiform Mole Coexisting with Two Fetuses after Ovulation Induction and Intrauterine Insemination
Gynecology Obstetrics & Reproductive Medicine
Triplet pregnancy
Partial hydatidiform mole
Ovulation induction
Intrauterine insemination
title Triplet Pregnancy with Partial Hydatidiform Mole Coexisting with Two Fetuses after Ovulation Induction and Intrauterine Insemination
title_full Triplet Pregnancy with Partial Hydatidiform Mole Coexisting with Two Fetuses after Ovulation Induction and Intrauterine Insemination
title_fullStr Triplet Pregnancy with Partial Hydatidiform Mole Coexisting with Two Fetuses after Ovulation Induction and Intrauterine Insemination
title_full_unstemmed Triplet Pregnancy with Partial Hydatidiform Mole Coexisting with Two Fetuses after Ovulation Induction and Intrauterine Insemination
title_short Triplet Pregnancy with Partial Hydatidiform Mole Coexisting with Two Fetuses after Ovulation Induction and Intrauterine Insemination
title_sort triplet pregnancy with partial hydatidiform mole coexisting with two fetuses after ovulation induction and intrauterine insemination
topic Triplet pregnancy
Partial hydatidiform mole
Ovulation induction
Intrauterine insemination
url https://gorm.com.tr/index.php/GORM/article/view/13
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