Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient
Cryptococcosis usually occurs in immunocompromised patients and presents as meningitis and lung disease. Adrenal gland involvement may be observed, yet primary adrenal insufficiency by cryptococcal infection is infrequent. We present a case of a middle-aged immunocompetent man with primary adrenal i...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-04-01
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| Series: | Indian Journal of Pathology and Microbiology |
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| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_185_22 |
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| author | Ramneek Kaur Naveen Mittal Ankita Soni Harpreet Kaur |
| author_facet | Ramneek Kaur Naveen Mittal Ankita Soni Harpreet Kaur |
| author_sort | Ramneek Kaur |
| collection | DOAJ |
| description | Cryptococcosis usually occurs in immunocompromised patients and presents as meningitis and lung disease. Adrenal gland involvement may be observed, yet primary adrenal insufficiency by cryptococcal infection is infrequent. We present a case of a middle-aged immunocompetent man with primary adrenal insufficiency and bilateral adrenal lesions, splenomegaly, and miliary mottling in the lungs on imaging. No evidence of meningitis was witnessed. The clinico-radiological findings led toward the differential diagnosis of disseminated tuberculosis or fungal infection. Detection of cryptococcus organism was done on fine-needle aspiration cytology and biopsy on periodic acid-Schiff stain and Gomori`s methenamine silver stain. Thus, it is recommended to keep the possibility of cryptococcosis in mind while dealing with instances that have a tuberculosis-like clinico-radiological presentation. The detection of the causal organism on Fine needle aspiration (FNA)/biopsy examination may be useful in confirming the diagnosis and determining the appropriate medical treatment. |
| format | Article |
| id | doaj-art-95fd24d369954be2838ecd89f12661c0 |
| institution | Kabale University |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-95fd24d369954be2838ecd89f12661c02025-02-07T14:00:56ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-04-0167243844010.4103/ijpm.ijpm_185_22Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patientRamneek KaurNaveen MittalAnkita SoniHarpreet KaurCryptococcosis usually occurs in immunocompromised patients and presents as meningitis and lung disease. Adrenal gland involvement may be observed, yet primary adrenal insufficiency by cryptococcal infection is infrequent. We present a case of a middle-aged immunocompetent man with primary adrenal insufficiency and bilateral adrenal lesions, splenomegaly, and miliary mottling in the lungs on imaging. No evidence of meningitis was witnessed. The clinico-radiological findings led toward the differential diagnosis of disseminated tuberculosis or fungal infection. Detection of cryptococcus organism was done on fine-needle aspiration cytology and biopsy on periodic acid-Schiff stain and Gomori`s methenamine silver stain. Thus, it is recommended to keep the possibility of cryptococcosis in mind while dealing with instances that have a tuberculosis-like clinico-radiological presentation. The detection of the causal organism on Fine needle aspiration (FNA)/biopsy examination may be useful in confirming the diagnosis and determining the appropriate medical treatment.https://journals.lww.com/10.4103/ijpm.ijpm_185_22adrenaladrenal infectioncryptococcustuberculosis |
| spellingShingle | Ramneek Kaur Naveen Mittal Ankita Soni Harpreet Kaur Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient Indian Journal of Pathology and Microbiology adrenal adrenal infection cryptococcus tuberculosis |
| title | Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient |
| title_full | Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient |
| title_fullStr | Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient |
| title_full_unstemmed | Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient |
| title_short | Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient |
| title_sort | bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient |
| topic | adrenal adrenal infection cryptococcus tuberculosis |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_185_22 |
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